(Q37352984)

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Biological implications of the ribosome's stunning stereochemistry

scientific article published on January 2009

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Europe PubMed Central

19 August 2017

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Europe PubMed Central

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Biological implications of the ribosome's stunning stereochemistry (English)

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stated in

Europe PubMed Central

19 August 2017

2

Ada Yonath

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stated in

Europe PubMed Central

19 August 2017

1

Ella Zimmerman

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stated in

Europe PubMed Central

19 August 2017

1 January 2009

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stated in

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

10

1 reference

stated in

Europe PubMed Central

19 August 2017

1

1 reference

stated in

Europe PubMed Central

19 August 2017

63-72

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stated in

Europe PubMed Central

19 August 2017

Structure of the 70S ribosome complexed with mRNA and tRNA

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structure of Bacterial Ribosomes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The ribosome as an entropy trap

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The interaction between C75 of tRNA and the A loop of the ribosome stimulates peptidyl transferase activity

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Antibiotics and the ribosome.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The real-time path of translation factor IF3 onto and off the ribosome.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Essential mechanisms in the catalysis of peptide bond formation on the ribosome.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Participation of the tRNA A76 hydroxyl groups throughout translation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Crystal structure of the ribosome at 5.5 A resolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Wobble during decoding: more than third-position promiscuity.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The structural basis of ribosome activity in peptide bond synthesis

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Rapid peptide bond formation on isolated 50S ribosomal subunits

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structural basis for messenger RNA movement on the ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Two distinct conformations of the conserved RNA-rich decoding center of the small ribosomal subunit are recognized by tRNAs and release factors.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Translation initiation: structures, mechanisms and evolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Unusual resistance of peptidyl transferase to protein extraction procedures

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The transition state for formation of the peptide bond in the ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Symmetry at the active site of the ribosome: structural and functional implications

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structures of the bacterial ribosome at 3.5 A resolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Toward ribosomal RNA catalytic activity in the absence of protein

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

A click chemistry approach to pleuromutilin conjugates with nucleosides or acyclic nucleoside derivatives and their binding to the bacterial ribosome.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structural insights into peptide bond formation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

A small particulate component of the cytoplasm

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Ribosomal tolerance and peptide bond formation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The ribosomal peptidyl transferase

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Analysis of predictions for the catalytic mechanism of ribosomal peptidyl transfer

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Mechanism of ribosomal peptide bond formation.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

tRNA selection and kinetic proofreading in translation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

High-resolution structures of large ribosomal subunits from mesophilic eubacteria and halophilic archaea at various functional States

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

What are the roles of substrate-assisted catalysis and proximity effects in peptide bond formation by the ribosome?

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The linkage between ribosomal crystallography, metal ions, heteropolytungstates and functional flexibility

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Correlating ribosome function with high-resolution structures

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structure of ribosomal RNA

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structure of a purine-purine wobble base pair in the decoding center of the ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Novel mutations in ribosomal proteins L4 and L22 that confer erythromycin resistance in Escherichia coli

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Ribosomal crystallography: from poorly diffracting microcrystals to high-resolution structures

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Involvement of RNA in the synthesis of proteins

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Signal transduction. Protein synthesis and oncogenesis meet again

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Altered methylation of ribosomal RNA in an erythromycin-resistant strain of Staphylococcus aureus

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Ribosomal antibiotics: structural basis for resistance, synergism and selectivity

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The ribosome as a drug target

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

The ribosomal peptidyl transferase center: structure, function, evolution, inhibition

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Peptide-bond synthesis on the ribosome: no free vicinal hydroxy group required on the terminal ribose residue of peptidyl-tRNA.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structural insights into the roles of water and the 2' hydroxyl of the P site tRNA in the peptidyl transferase reaction

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Substrate-assisted catalysis of peptide bond formation by the ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Peptide bond formation destabilizes Shine-Dalgarno interaction on the ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

High resolution structure of the large ribosomal subunit from a mesophilic eubacterium

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/CBIC.200800554

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10.1002/CBIC.200800554

1 reference

stated in

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

PubMed ID

19089882

retrieved

19 August 2017

(Q37352984)

Biological implications of the ribosome's stunning stereochemistry

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