(Q37358987)

19 August 2017

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title

Autoimmune diabetes mellitus--much progress, but many challenges (English)

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19 August 2017

2

Emil R Unanue

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19 August 2017

Hugh O McDevitt

1

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19 August 2017

publication date

1 January 2008

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19 August 2017

published in

Advances in Immunology

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19 August 2017

volume

100

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19 August 2017

page(s)

1-12

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The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

19 August 2017

cites work

1 reference

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7 January 2021

Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules

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7 January 2021

Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

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7 January 2021

CD3-specific antibodies restore self-tolerance: mechanisms and clinical applications

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7 January 2021

CD3-specific antibodies: a portal to the treatment of autoimmunity

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

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7 January 2021

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

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7 January 2021

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

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7 January 2021

Insulin autoimmunity: prediction/precipitation/prevention type 1A diabetes

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7 January 2021

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice

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7 January 2021

Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse

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7 January 2021

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

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7 January 2021

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

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7 January 2021

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

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7 January 2021

Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes

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7 January 2021

Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction

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7 January 2021

Following a diabetogenic T cell from genesis through pathogenesis

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7 January 2021

A defect in central tolerance in NOD mice

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7 January 2021

Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice

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7 January 2021

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

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A comprehensive guide to antibody and T-cell responses in type 1 diabetes.

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Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.

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7 January 2021

Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse

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7 January 2021

Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response

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7 January 2021

Studies of streptozotocin-induced insulitis and diabetes

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7 January 2021

Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity?

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7 January 2021

Insulin-dependent diabetes mellitus

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7 January 2021

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

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7 January 2021

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

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7 January 2021

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

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7 January 2021

Type 1 diabetes genes and pathways shared by humans and NOD mice

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7 January 2021

Insulin as an autoantigen in NOD/human diabetes

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7 January 2021

Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2).

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7 January 2021

Identification of immunogenic epitopes of GAD 65 presented by Ag7 in non-obese diabetic mice

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7 January 2021

10.1016/S0065-2776(08)00801-8

Identifiers

DOI

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19 August 2017

1 reference