(Q37360851)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

The mechanical integrin cycle (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Eileen Puklin-Faucher

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Michael P Sheetz

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

1 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Journal of Cell Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

179-186

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

Pt 2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

Receptor protein tyrosine phosphatase alpha activates Src-family kinases and controls integrin-mediated responses in fibroblasts

19 January 2020

cites work

1 reference

12 December 2020

Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc.

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12 December 2020

Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function

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12 December 2020

Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

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12 December 2020

Cell spreading and lamellipodial extension rate is regulated by membrane tension

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12 December 2020

Position-dependent linkages of fibronectin- integrin-cytoskeleton

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12 December 2020

Integrin dynamics and matrix assembly: tensin-dependent translocation of alpha(5)beta(1) integrins promotes early fibronectin fibrillogenesis

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12 December 2020

Physical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesions

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12 December 2020

Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts

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12 December 2020

Identification of shc as the primary protein binding to the tyrosine-phosphorylated beta 3 subunit of alpha IIbbeta 3 during outside-in integrin platelet signaling

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12 December 2020

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

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12 December 2020

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

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12 December 2020

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

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12 December 2020

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

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12 December 2020

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

1 reference

12 December 2020

Integrin tyrosine phosphorylation in platelet signaling

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12 December 2020

Crystal structure of the extracellular segment of integrin alpha Vbeta3

1 reference

12 December 2020

Localization of an integrin binding site to the C terminus of talin

1 reference

12 December 2020

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

1 reference

12 December 2020

Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior

1 reference

12 December 2020

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

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12 December 2020

Integrin activation takes shape

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12 December 2020

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

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12 December 2020

Integrins: bidirectional, allosteric signaling machines

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12 December 2020

The relationship between force and focal complex development

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12 December 2020

Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion

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12 December 2020

Structural determinants of integrin recognition by talin

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12 December 2020

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand

1 reference

12 December 2020

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling

1 reference

12 December 2020

Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

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12 December 2020

RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages

1 reference

12 December 2020

Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

1 reference

12 December 2020

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

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12 December 2020

Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts

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12 December 2020

Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2

1 reference

12 December 2020

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

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12 December 2020

Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

1 reference

12 December 2020

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

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12 December 2020

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

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12 December 2020

Periodic lamellipodial contractions correlate with rearward actin waves

1 reference

12 December 2020

A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain

1 reference

12 December 2020

Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain

1 reference

12 December 2020

Cell mechanosensitivity controls the anisotropy of focal adhesions

1 reference

12 December 2020

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

1 reference

12 December 2020

The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells

1 reference

12 December 2020

Activation of a signaling cascade by cytoskeleton stretch

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12 December 2020

The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2.

1 reference

12 December 2020

A specific alpha5beta1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation.

1 reference

12 December 2020

Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin

1 reference

12 December 2020

Focal adhesions as mechanosensors: a physical mechanism.

1 reference

12 December 2020

Syndecan recycling [corrected] is controlled by syntenin-PIP2 interaction and Arf6.

1 reference

12 December 2020

Is the mechanical activity of epithelial cells controlled by deformations or forces?

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12 December 2020

The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells

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12 December 2020

Tissue cells feel and respond to the stiffness of their substrate

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12 December 2020

Rigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha

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12 December 2020

The molecular basis of filamin binding to integrins and competition with talin

1 reference

12 December 2020

Displacement of the {beta} cytoplasmic domain recovers focal adhesion formation, cytoskeletal organization and motility in swapped integrin chimeras.

1 reference

12 December 2020

Force-induced adsorption and anisotropic growth of focal adhesions

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12 December 2020

Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways

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12 December 2020

Lateral spacing of integrin ligands influences cell spreading and focal adhesion assembly

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12 December 2020

In vivo beta1 integrin function requires phosphorylation-independent regulation by cytoplasmic tyrosines

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12 December 2020

An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton.

1 reference

12 December 2020

Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow

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12 December 2020

How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation

1 reference

12 December 2020

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

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12 December 2020

Differential transmission of actin motion within focal adhesions

1 reference

12 December 2020

Structural basis of integrin activation by talin

1 reference

12 December 2020

Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells

1 reference

12 December 2020

Lamellipodial actin mechanically links myosin activity with adhesion-site formation

1 reference

12 December 2020

Polymerizing actin fibers position integrins primed to probe for adhesion sites

1 reference

12 December 2020

The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton

1 reference

12 December 2020

alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration.

1 reference

12 December 2020

Structural basis for the autoinhibition of focal adhesion kinase

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12 December 2020

Integrin modulation and signaling in leukocyte adhesion and migration

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12 December 2020

Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces

1 reference

12 December 2020

Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals

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12 December 2020

RPTPalpha is required for rigidity-dependent inhibition of extension and differentiation of hippocampal neurons.

1 reference

12 December 2020

α-Actinin: a direct link between actin and integrins

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12 December 2020

Synergistic control of cell adhesion by integrins and syndecans.

1 reference

12 December 2020

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

1 reference

12 December 2020

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins

1 reference

12 December 2020

Quantification of integrin receptor agonism by fluorescence lifetime imaging

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12 December 2020

Kindlin-3 is essential for integrin activation and platelet aggregation

1 reference

12 December 2020

How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism

1 reference

12 December 2020

1 reference

12 December 2020

Kindlin-2 (Mig-2): a co-activator of beta3 integrins.

1 reference

12 December 2020

Differences in regulation of Drosophila and vertebrate integrin affinity by talin

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12 December 2020

Binding of soluble fibronectin to integrin alpha5 beta1 - link to focal adhesion redistribution and contractile shape.

1 reference

12 December 2020

Cooperativity in adhesion cluster formation during initial cell adhesion

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12 December 2020

Comparative dynamics of retrograde actin flow and focal adhesions: formation of nascent adhesions triggers transition from fast to slow flow

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12 December 2020

Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading

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12 December 2020

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

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12 December 2020

Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion

1 reference

12 December 2020

Focal adhesion formation by F9 embryonal carcinoma cells after vinculin gene disruption.

1 reference

12 December 2020

Integrin-cytoskeletal interactions in neuronal growth cones

1 reference

12 December 2020

Integrin-cytoskeletal interactions in migrating fibroblasts are dynamic, asymmetric, and regulated

1 reference

12 December 2020

Requirement of integrin beta3 tyrosine 747 for beta3 tyrosine phosphorylation and regulation of alphavbeta3 avidity

1 reference

12 December 2020

Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells

1 reference

12 December 2020

Energy landscapes of receptor-ligand bonds explored with dynamic force spectroscopy

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.042127

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19118210%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference