(Q37366206)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

2

1 reference

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29 January 2020

R. Kiplin Guy

8

1 reference

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29 January 2020

1

Jong Yeon Hwang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

3

Fangyi Zhu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

4

Aaron Kosinski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Thomas J Mangano

5

1 reference

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29 January 2020

Vincent Setola

6

1 reference

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29 January 2020

Bryan L Roth

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

1 July 2009

1 reference

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29 January 2020

number of pages

10

1 reference

Journal of Medicinal Chemistry

inferred from page(s)

published in

1 reference

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29 January 2020

volume

52

1 reference

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29 January 2020

page(s)

3892-3901

1 reference

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29 January 2020

issue

13

1 reference

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Structural insight into the mode of action of a direct inhibitor of coregulator binding to the thyroid hormone receptor

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

High throughput solubility measurement in drug discovery and development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Thyroid hormones signaling is getting more complex: STORMs are coming

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Thyroid hormone ligands and metabolic diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Mechanism of thyroid hormone action

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

A thyroid hormone antagonist that inhibits thyroid hormone action in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Tissue-specific actions of thyroid hormone: insights from animal models

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Nuclear hormone receptors and gene expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Physiological and molecular basis of thyroid hormone action

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Cloning and characterization of two novel thyroid hormone receptor beta isoforms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

The nuclear receptor superfamily: the second decade

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Benzylic hydroxylation of 1-methylpyrene and 1-ethylpyrene by human and rat cytochromes P450 individually expressed in V79 Chinese hamster cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Access and binding of local anesthetics in the closed sodium channel

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Chemical aspects of metoprolol metabolism. Asymmetric synthesis and absolute configuration of the 3-[4-(1-hydroxy-2-methoxyethyl)phenoxy]-1-(isopropylamino)-2-propanols , the diastereomeric benzylic hydroxylation metabolites

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Design and synthesis of complementing ligands for mutant thyroid hormone receptor TRbeta(R320H): a tailor-made approach toward the treatment of resistance to thyroid hormone

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Cardiotoxic and antiarrhythmic tertiary amine local anesthetics: sodium channel affinity vs. sodium channel gating.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Efficient large scale microwave assisted Mannich reactions using substituted acetophenones

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Mechanisms of thyroid hormone action: insights from X-ray crystallographic and functional studies.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753520

Microwave-assisted Mannich-type three-component reactions

2 September 2018

1 reference

12 December 2020

Biopharmaceutics classification by high throughput solubility assay and PAMPA

1 reference

12 December 2020

A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding

1 reference

12 December 2020

Design, synthesis, and pharmacological evaluation of R/S-3,4-dihydro-2,2-dimethyl- 6-halo-4-(phenylaminocarbonylamino)-2H-1-benzopyrans: toward tissue-selective pancreatic beta-cell KATP channel openers structurally related to (+/-)-cromakalim

1 reference

12 December 2020

Mimicry of phase I drug metabolism--novel methods for metabolite characterization and synthesis

1 reference

12 December 2020

Is PAMPA a useful tool for discovery?

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM9002704

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19469546%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference