(Q37368860)

20 August 2017

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation (English)

1 reference

DNA topoisomerase III-beta-TDRD3 complex

20 August 2017

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0140225

RNA topoisomerase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0140226

Topoisomerase 3beta Dmel_CG3458

1 reference

GOA release 2020-03-11

1 reference

Subramanya Srikantan

9

0 references

Dongyi Xu

Dongyi Xu

1

0 references

Thomas E. Lloyd

Thomas E Lloyd

19

0 references

Grant W Brown

Grant W Brown

20

0 references

Myriam Gorospe

22

Myriam Gorospe

1 reference

20 August 2017

Jennifer L Martindale

13

Jennifer L Martindale

1 reference

20 August 2017

14

Yulan Piao

1 reference

20 August 2017

Weiping Shen

2

1 reference

20 August 2017

Rong Guo

3

1 reference

20 August 2017

Yutong Xue

4

1 reference

20 August 2017

Wei Peng

5

1 reference

20 August 2017

Jian Sima

6

1 reference

20 August 2017

Jay Yang

7

1 reference

20 August 2017

Alexei Sharov

8

1 reference

20 August 2017

Jiandong Yang

10

1 reference

20 August 2017

David Fox

11

1 reference

20 August 2017

Yong Qian

12

1 reference

20 August 2017

James Machamer

15

1 reference

20 August 2017

Samit R Joshi

16

1 reference

20 August 2017

Subhasis Mohanty

17

1 reference

20 August 2017

Albert C Shaw

18

1 reference

20 August 2017

Minoru S H Ko

21

1 reference

20 August 2017

Sige Zou

23

1 reference

20 August 2017

Weidong Wang

24

1 reference

20 August 2017

language of work or name

English

0 references

publication date

4 August 2013

1 reference

20 August 2017

1 reference

20 August 2017

16

1 reference

20 August 2017

9

1 reference

20 August 2017

1238-1247

1 reference

describes a project that uses

20 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3853347/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nn.3479

0 references

cites work

Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Circular RNAs are a large class of animal RNAs with regulatory potency

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Natural RNA circles function as efficient microRNA sponges

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

FMRP targets distinct mRNA sequence elements to regulate protein expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Diverse types of genetic variation converge on functional gene networks involved in schizophrenia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Family history of schizophrenia and bipolar disorder as risk factors for autism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

De Novo Gene Disruptions in Children on the Autistic Spectrum

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

The pathophysiology of fragile X (and what it teaches us about synapses)

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Genome-wide association study identifies five new schizophrenia loci

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Eukaryotic stress granules: the ins and outs of translation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Genetic modifiers of dFMR1 encode RNA granule components in Drosophila

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

RNA pseudoknots and the regulation of protein synthesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Development of autoimmunity in mice lacking DNA topoisomerase 3beta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Whole-genome re-sequencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

A new Drosophila gene wh (wuho) with WD40 repeats is essential for spermatogenesis and has maximal expression in hub cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Hairpin RNA: a secondary structure of primary importance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Tudor domains bind symmetrical dimethylated arginines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Fragile X protein functions with lgl and the par complex in flies and mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Drosophila melanogaster topoisomerase IIIalpha preferentially relaxes a positively or negatively supercoiled bubble substrate and is essential during development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Control of axonal branching and synapse formation by focal adhesion kinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Cellular roles of dna topoisomerases: a molecular perspective

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Circularization of mRNA by eukaryotic translation initiation factors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Differential Expressions of Synaptogenic Markers between Primary Cultured Cortical and Hippocampal Neurons

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

FMRP is associated to the ribosomes via RNA.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

The fragile X mental retardation protein is associated with ribosomes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Cloning and characterization of Drosophila topoisomerase IIIbeta. Relaxation of hypernegatively supercoiled DNA.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853347

Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNN.3479

Expression of DFak56, a Drosophila homolog of vertebrate focal adhesion kinase, supports a role in cell migration in vivo

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNN.3479

Microscopic analysis of the adult Drosophila retina using semithin plastic sections.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNN.3479

21 January 2018

Identifiers

DOI

10.1038/NN.3479

1 reference

Dimensions Publication ID

20 August 2017

0 references

1 reference

20 August 2017

PubMed publication ID

23912945

1 reference