(Q37371868)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

review article

1 reference

title

The function of ROCO proteins in health and disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Patrick A Lewis

series ordinal

1

1 reference

20 August 2017

language of work or name

1 reference

1 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Biology of the Cell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

183-191

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19152505%20AND%20SRC:MED&resulttype=core&format=json

The identification of pats1, a novel gene locus required for cytokinesis in Dictyostelium discoideum

20 January 2020

cites work

1 reference

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Raf meets Ras: completing the framework of a signal transduction pathway

21 January 2018

1 reference

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The death-associated protein kinases: structure, function, and beyond

21 January 2018

1 reference

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Localization of LRRK2 to membranous and vesicular structures in mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Roc, a Ras/GTPase domain in complex proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

ERM-Merlin and EBP50 protein families in plasma membrane organization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Identification of potential protein interactors of Lrrk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

GRAM, a novel domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Recent advances in understanding signal transduction pathways in worms and flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Identification of four candidate cGMP targets in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Patterns of somatic mutation in human cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Leucine-rich repeat kinase 2 associates with lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Two pools of Triton X-100-insoluble GABA(A) receptors are present in the brain, one associated to lipid rafts and another one to the post-synaptic GABAergic complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

DAPK1 variants are associated with Alzheimer's disease and allele-specific expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

A Drosophila model for LRRK2-linked parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Kinase activity of mutant LRRK2 mediates neuronal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Investigating convergent actions of genes linked to familial Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

Mechanistic insight into the dominant mode of the Parkinson's disease-associated G2019S LRRK2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053

DAP kinase links the control of apoptosis to metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBC20080053