(Q37372782)

English

Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft.

scientific article published on 06 May 2009

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19418039%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19418039%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

type-1 diabetes

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immunosuppression

1 reference

based on heuristic

inferred from title

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Bradford J. Wood

5

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27 January 2020

author name string

E H Liu

1

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27 January 2020

B J Digon

2

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27 January 2020

B Hirshberg

3

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27 January 2020

R Chang

4

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27 January 2020

Z Neeman

6

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27 January 2020

A Kam

7

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27 January 2020

R A Wesley

8

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27 January 2020

S M Polly

9

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27 January 2020

R M Hofmann

10

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27 January 2020

K I Rother

11

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27 January 2020

D M Harlan

12

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27 January 2020

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publication date

6 May 2009

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27 January 2020

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27 January 2020

52

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27 January 2020

7

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27 January 2020

1369-1380

1 reference

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27 January 2020

https://scigraph.springernature.com/pub.10.1007/s00125-009-1342-7

0 references

Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

T cell-directed therapies: lessons learned and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Extrapancreatic insulin-producing cells in multiple organs in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Disappearance of humoral thyroid autoimmunity after complete removal of thyroid antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Reversal of established autoimmune diabetes by restoration of endogenous beta cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Islet growth and development in the adult

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

Islet cell survival determined by morphology. An immunocytochemical study of the islets of Langerhans in juvenile diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

6 September 2017

The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

14 September 2017

Factors of Importance for Residual Beta-cell Function in Type I Diabetes Mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

14 September 2017

Persistent insulin secretion, assessed by plasma C-peptide estimation in long-term juvenile diabetics with a low insulin requirement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

28 September 2017

Prevalence of residual beta-cell function in insulin-dependent diabetics in relation to age at onset and duration of diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

28 September 2017

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

26 June 2018

Growth and regeneration of adult beta cells does not involve specialized progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Beta-cell growth: an unusual paradigm of organogenesis that is cyclin D2/Cdk4 dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Increased vulnerability of newly forming beta cells to cytokine-induced cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Very slow turnover of beta-cells in aged adult mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Complete long-term recovery of beta-cell function in autoimmune type 1 diabetes after insulin treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Islet antibodies and remaining beta-cell function 8 years after diagnosis of diabetes in young adults: a prospective follow-up of the nationwide Diabetes Incidence Study in Sweden

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Sirolimus-Induced Interstitial Pneumonitis in an Islet Transplant Recipient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Protection from type 1 diabetes in the face of high levels of activated autoaggressive lymphocytes in a viral transgenic mouse model crossed to the SV129 strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

beta-cell turnover: its assessment and implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 September 2018

Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756111

2 October 2018

β-Cell Regeneration in a Patient with Type 1 Diabetes Mellitus Who Was Receiving Immunosuppressive Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of Endocrine Cell Content in the Pancreas of Nondiabetic and Diabetic Humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of residual B cell function and its metabolic consequences in Type 1 (insulin-dependent) diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential Sensitivity to β-Cell Secretagogues in “Early,” Type I Diabetes Mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet morphology in type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Residual insulin positivity and pancreatic atrophy in relation to duration of chronic Type 1 (insulin-dependent) diabetes mellitus and microangiopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic autoimmunity of type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent GAD 65 antibodies in longstanding IDDM are not associated with residual beta-cell function, neuropathy or HLA-DR status

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. The Diabetes Control and Complications Trial Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Successful islet autotransplantation in humans: functional insulin secretory reserve as an estimate of surviving islet cell mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of GAD and ICA512/IA-2 antibodies at and after the onset of IDDM

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of autoimmunity and immune therapy on beta-cell turnover in type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19418039

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-009-1342-7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19418039%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19418039%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19418039%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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