(Q37377149)

20 August 2017

1 reference

title

The importance of radiation chemistry to radiation and free radical biology (The 2008 Silvanus Thompson Memorial Lecture). (English)

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20 August 2017

P Wardman

1

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PubMed ID

19168690

20 August 2017

language of work or name

English

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publication date

1 February 2009

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British Journal of Radiology

20 August 2017

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20 August 2017

82

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20 August 2017

974

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20 August 2017

89-104

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Intensity-modulated radiation therapy (IMRT): a clinical reality for cancer treatment, "any fool can understand this". The 2004 Silvanus Thompson Memorial Lecture.

20 August 2017

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Redox signaling mechanisms and radiation-induced bystander effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Oxidative damage pathways in relation to normal tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Signaling factors for irradiated glioma cells induced bystander responses in fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Low-dose irradiation of nontransformed cells stimulates the selective removal of precancerous cells via intercellular induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Regulation of HIF-1alpha stability through S-nitrosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Hypoxic radiosensitization: adored and ignored

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Chemical radiosensitizers for use in radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

HIF-1 and tumour radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Rapid Mixing in Radiobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Radiation-induced DNA Strand Breaks in Deoxygenated Aqueous Solutions. The Formation of Altered Sugars as End Groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

The Reaction of Oxygen with Radiation-induced Free Radicals in DNA and Related Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

The Effects of Counter-ion Condensation and Co-ion Depletion Upon the Rates of Chemical Repair of Poly(U) Radicals by Thiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

On the chemical yield of base lesions, strand breaks, and clustered damage generated in plasmid DNA by the direct effect of X rays

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Sugar radicals in DNA: isolation of neutral radicals in gamma-irradiated DNA by hole and electron scavenging

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Competitive dose-modification between ascorbate and misonidazole in human and hamster cells: effects of glutathione depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Mechanisms of protein damage induced by cysteine thiyl radical formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Trans lipids: the free radical path

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Sunscreens inadequately protect against ultraviolet-A-induced free radicals in skin: implications for skin aging and melanoma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Radicals from one-electron reduction of nitro compounds, aromatic N-oxides and quinones: the kinetic basis for hypoxia-selective, bioreductive drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Pharmacokinetic/pharmacodynamic model-guided identification of hypoxia-selective 1,2,4-benzotriazine 1,4-dioxides with antitumor activity: the role of extravascular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Oxygen inhibition of nitroreductase: Electron transfer from nitro radical-anions to oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Preparation, toxicity and mutagenicity of 1-methyl-2-nitrosoimidazole. A toxic 2-nitroimidazole reduction product

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Kinetics of the reactions of nitrogen dioxide with glutathione, cysteine, and uric acid at physiological pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Reactions of PTIO and carboxy-PTIO with *NO, *NO2, and O2-*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Structure-activity relationships in the development of hypoxic cell radiosensitizers. I. Sensitization efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

The role of hypoxia-activated prodrugs in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Exploiting tumour hypoxia in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Activation of 3-amino-1,2,4-benzotriazine 1,4-dioxide antitumor agents to oxidizing species following their one-electron reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Oxidation of 2-deoxyribose by benzotriazinyl radicals of antitumor 3-amino-1,2,4-benzotriazine 1,4-dioxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Use of the dichlorofluorescein assay to measure "reactive oxygen species".

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Effect of nitric oxide on the radiosensitivity of bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Radiosensitization by nitric oxide at low radiation doses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

p21((WAF1))-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

The radiosensitizing effect of immunoadjuvant OM-174 requires cooperation between immune and tumor cells through interferon-gamma and inducible nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Nitric oxide as a cellular antioxidant: a little goes a long way.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Oxidative activation of indole-3-acetic acids to cytotoxic species- a potential new role for plant auxins in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

A systems biology approach to multicellular and multi-generational radiation responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Systems biology and its potential role in radiobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

New insights on cell death from radiation exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Untargeted effects of ionizing radiation: implications for radiation pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

The initiation and development of cellular damage by ionizing radiations; the thirty-second Silvanus Thompson Memorial Lecture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Pitfalls in the Use of Common Luminescent Probes for Oxidative and Nitrosative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Measurement of Tumor Oxygenation: A Comparison between Polarographic Needle Electrodes and a Time-Resolved Luminescence-Based Optical Sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Absorption Spectra in Irradiated Water and Some Solutions: Absorption Spectra of ‘Hydrated’ Electron

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Electron Spin Resonance in Irradiated Deoxyribonucleic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

Effect of Nitric Oxide on the Radio-sensitivity of Tumour Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1259%2FBJR%2F60186130

21 January 2018

Identifiers

DOI

10.1259/BJR/60186130

1 reference

20 August 2017

1 reference

PubMed ID

19168690