(Q37379647)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

title

Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

Middle East respiratory syndrome coronavirus

26 March 2020

main subject

0 references

1 reference

Middle East respiratory syndrome coronavirus

1 reference

1 reference

Middle East respiratory syndrome

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Anthony R Fehr

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Stanley Perlman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Paul B McCray

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

3

Arlene Barlan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

author name string

Kun Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Tom Gallagher

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

language of work or name

English

0 references

publication date

10 October 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

26 March 2020

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

volume

113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

issue

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

page(s)

12262-12267

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

Pre-fusion structure of a human coronavirus spike protein.

26 March 2020

cites work

1 reference

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Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak

6 September 2017

1 reference

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Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer

6 September 2017

1 reference

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The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung

6 September 2017

1 reference

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MERS-CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia, 2013-2014

6 September 2017

1 reference

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Protease inhibitors targeting coronavirus and filovirus entry

6 September 2017

1 reference

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Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

6 September 2017

1 reference

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Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

6 September 2017

1 reference

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Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

6 September 2017

1 reference

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Inhibition of proprotein convertases abrogates processing of the middle eastern respiratory syndrome coronavirus spike protein in infected cells but does not reduce viral infectivity.

6 September 2017

1 reference

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Rapid generation of a mouse model for Middle East respiratory syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

First infection by all four non-severe acute respiratory syndrome human coronaviruses takes place during childhood

6 September 2017

1 reference

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Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Mutation in spike protein cleavage site and pathogenesis of feline coronavirus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Role of host cellular proteases in the pathogenesis of influenza and influenza-induced multiple organ failure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

6 September 2017

1 reference

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A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2.

6 September 2017

1 reference

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Elastase-mediated activation of the severe acute respiratory syndrome coronavirus spike protein at discrete sites within the S2 domain

6 September 2017

1 reference

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Two-step conformational changes in a coronavirus envelope glycoprotein mediated by receptor binding and proteolysis

6 September 2017

1 reference

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Proteolytic activation of the spike protein at a novel RRRR/S motif is implicated in furin-dependent entry, syncytium formation, and infectivity of coronavirus infectious bronchitis virus in cultured cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites

6 September 2017

1 reference

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Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus

6 September 2017

1 reference

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Bats are natural reservoirs of SARS-like coronaviruses

6 September 2017

1 reference

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Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats

6 September 2017

1 reference

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Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Wet markets--a continuing source of severe acute respiratory syndrome and influenza?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Synthesis and characterization of a native, oligomeric form of recombinant severe acute respiratory syndrome coronavirus spike glycoprotein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

A virus-binding hot spot on human angiotensin-converting enzyme 2 is critical for binding of two different coronaviruses

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell-cell fusion but does not affect virion entry.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

An in vitro model of differentiated human airway epithelia. Methods for establishing primary cultures.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Efficient synthetic method for ethyl (+)-(2S,3S)-3-[(S)-3-methyl- 1-(3-methylbutylcarbamoyl)butylcarbamoyl]-2-oxiranecarb oxylate (EST), a new inhibitor of cysteine proteinases

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

Severe acute respiratory syndrome

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5086990

2 October 2018

Identifiers

DOI

10.1073/PNAS.1608147113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

release_lhwaug6qijfwxodpsvdxa7jmpq

26 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lhwaug6qijfwxodpsvdxa7jmpq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27791014%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

PubMed publication ID

27791014

1 reference