(Q37386837)

20 August 2017

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title

Antioxidant and pro-oxidant capacities of ITCs (English)

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20 August 2017

Luca Valgimigli

1

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author name string

Renato Iori

series ordinal

2

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20 August 2017

publication date

1 April 2009

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Environmental and Molecular Mutagenesis

20 August 2017

published in

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20 August 2017

volume

50

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20 August 2017

issue

3

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20 August 2017

page(s)

222-237

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Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane

20 August 2017

cites work

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Studies on lipid peroxidation in normal and tumour tissues. The Novikoff rat liver tumour

21 January 2018

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Mechanism-based in vitro screening of potential cancer chemopreventive agents

21 January 2018

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Chemoprevention by isothiocyanates and their underlying molecular signaling mechanisms

21 January 2018

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Isothiocyanates as substrates for human glutathione transferases: structure-activity studies.

21 January 2018

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Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver

21 January 2018

1 reference

Cancer-preventive isothiocyanates: measurement of human exposure and mechanism of action.

21 January 2018

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A critical appraisal of the use of the antioxidant capacity (TEAC) assay in defining optimal antioxidant structures

21 January 2018

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7 January 2021

Stereoselective Synthesis of (+/-)-alpha-Kainic Acid Using Free Radical Key Reactions

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7 January 2021

Dual action of sulforaphane in the regulation of thioredoxin reductase and thioredoxin in human HepG2 and Caco-2 cells

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7 January 2021

CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane

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7 January 2021

Direct antioxidant activity of purified glucoerucin, the dietary secondary metabolite contained in rocket (Eruca sativa Mill.) seeds and sprouts

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7 January 2021

Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus sprouts (kaiware daikon) and its redox properties.

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7 January 2021

Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats

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7 January 2021

Kaiware Daikon (Raphanus sativus L.) extract: a naturally multipotent chemopreventive agent

1 reference

7 January 2021

Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells.

1 reference

7 January 2021

Cascade radical reaction of 2-alkynyl-substituted aryl radicals with aryl isothiocyanates: a novel entry to benzothieno[2,3-b]quinolines through alpha-(Arylsulfanyl)imidoyl radicals

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7 January 2021

Vitamin E as an in vitro and in vivo antioxidant

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7 January 2021

Cellular accumulation of dietary anticarcinogenic isothiocyanates is followed by transporter-mediated export as dithiocarbamates

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7 January 2021

Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: a structure-activity relationship study

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7 January 2021

Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli

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7 January 2021

Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast.

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7 January 2021

Cell-type specific differences in glutamate cysteine ligase transcriptional regulation demonstrate independent subunit control

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7 January 2021

Regulation and role of heme oxygenase in oxidative injury

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7 January 2021

Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen

1 reference

7 January 2021

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

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7 January 2021

The role of Keap1 in cellular protective responses

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7 January 2021

Antioxidant and co-antioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous multilamellar phospholipid liposomes

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7 January 2021

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

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7 January 2021

The chemical diversity and distribution of glucosinolates and isothiocyanates among plants

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7 January 2021

Glucosinolates and their breakdown products in food and food plants

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7 January 2021

Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage

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7 January 2021

Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane

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7 January 2021

Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an isothiocyanate structurally related to sulforaphane

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7 January 2021

Ageing, oxidative stress, and mitochondrial uncoupling.

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7 January 2021

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.

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7 January 2021

In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat.

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7 January 2021

Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice

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7 January 2021

Formation of glucoraphanin by chemoselective oxidation of natural glucoerucin: a chemoenzymatic route to sulforaphane

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7 January 2021

Evaluation of the antioxidant activity by flow injection analysis method with electrochemically generated ABTS radical cation

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7 January 2021

Pharmacokinetics of dietary phenethyl isothiocyanate in rats

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7 January 2021

Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates

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7 January 2021

Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China

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7 January 2021

3-Morpholinopropyl isothiocyanate is a novel synthetic isothiocyanate that strongly induces the antioxidant response element-dependent Nrf2-mediated detoxifying/antioxidant enzymes in vitro and in vivo

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7 January 2021

Evaluation of the safety and bioactivity of purified and semi-purified glucoraphanin.

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7 January 2021

Interindividual differences in phytochemical metabolism and disposition

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7 January 2021

Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane

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7 January 2021

Nrf2 as a novel molecular target for chemoprevention

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7 January 2021

Chemoprevention of acrylamide toxicity by antioxidative agents in rats--effective suppression of testicular toxicity by phenylethyl isothiocyanate

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7 January 2021

Oxidative conversion by rat liver microsomes of 2-naphthyl isothiocyanate to 2-naphthyl isocyanate, a genotoxicant

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7 January 2021

Enzyme induction and comparative oxidative desulfuration of isothiocyanates to isocyanates

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7 January 2021

Abnormal solvent effects on hydrogen atom abstractions. 1. The reactions of phenols with 2,2-diphenyl-1-picrylhydrazyl (dpph*) in alcohols

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7 January 2021

Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates

1 reference

7 January 2021

Metabolism of some naturally occurring isothiocyanates in the rat

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7 January 2021

Isothiocyanates. A new class of uncouplers

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7 January 2021

Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesis

1 reference

7 January 2021

Broccoli: a unique vegetable that protects mammalian hearts through the redox cycling of the thioredoxin superfamily

1 reference

7 January 2021

Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds

1 reference

7 January 2021

Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates.

1 reference

7 January 2021

Mechanism of oxidative DNA damage induced by carcinogenic allyl isothiocyanate

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7 January 2021

Thioredoxin reductase

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7 January 2021

Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis

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7 January 2021

The time-dependent effect of gluconasturtiin and phenethyl isothiocyanate on metabolic and antioxidative parameters in rats

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7 January 2021

Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli

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7 January 2021

Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.

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7 January 2021

Reactive oxygen species-related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to sulforaphane

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7 January 2021

Are whole extracts and purified glucosinolates from cruciferous vegetables antioxidants?

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7 January 2021

Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression

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7 January 2021

Chemical and molecular regulation of enzymes that detoxify carcinogens

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7 January 2021

Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation

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7 January 2021

Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells.

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7 January 2021

Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells

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7 January 2021

Quantitative measurement of the total, peroxyl radical-trapping antioxidant capability of human blood plasma by controlled peroxidation. The important contribution made by plasma proteins.

1 reference

7 January 2021

Reaction of phenylaminoethyl selenides with peroxynitrite and hydrogen peroxide

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7 January 2021

The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats

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7 January 2021

Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system

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7 January 2021

Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro

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7 January 2021

Total intracellular accumulation levels of dietary isothiocyanates determine their activity in elevation of cellular glutathione and induction of Phase 2 detoxification enzymes

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7 January 2021

Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans

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7 January 2021

Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme

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7 January 2021

Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity

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7 January 2021

Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells.

1 reference

7 January 2021

Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates

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7 January 2021

Discovery and development of sulforaphane as a cancer chemopreventive phytochemical

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7 January 2021

Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases

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7 January 2021

Quantitative Determination of Isothiocyanates, Dithiocarbamates, Carbon Disulfide, and Related Thiocarbonyl Compounds by Cyclocondensation with 1,2-Benzenedithiol

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7 January 2021

Expression and regulation of glutathione S-transferase P1-1 in cultured human epidermal cells.

1 reference

7 January 2021

Cancer-preventive isothiocyanates: dichotomous modulators of oxidative stress

1 reference

7 January 2021

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

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7 January 2021

Identifiers

DOI

10.1002/EM.20468

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20 August 2017

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