(Q37388725)

20 August 2017

Structure-guided development of selective TbcatB inhibitors (English)

1 reference

20 August 2017

7

James H McKerrow

1 reference

20 August 2017

Anang A Shelat

2

0 references

R. Kiplin Guy

series ordinal

8

object named as

R Kiplin Guy

1 reference

20 August 2017

5

Michele Connelly

1 reference

20 August 2017

6

Fangyi Zhu

1 reference

20 August 2017

4

Conor R Caffrey

1 reference

20 August 2017

1

Jeremy P Mallari

1 reference

20 August 2017

3

Aaron Kosinski

1 reference

PMCID

2762491

20 August 2017

language of work or name

English

0 references

publication date

1 October 2009

1 reference

Journal of Medicinal Chemistry

20 August 2017

1 reference

20 August 2017

52

1 reference

20 August 2017

20

1 reference

20 August 2017

6489-6493

1 reference

RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Very fast empirical prediction and rationalization of protein pKa values

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

VMD: visual molecular dynamics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

External validation and prediction employing the predictive squared correlation coefficient test set activity mean vs training set activity mean.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762491

2 September 2018

Identifiers

DOI

10.1021/JM900908P

1 reference

20 August 2017

1 reference

20 August 2017

1 reference

PMCID

2762491