(Q37394018)

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The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation

scientific article published on June 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

20 August 2017

The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Nicholas R J Gascoigne

7

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Nicholas R J Gascoigne

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Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Michel Mallaun

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Dieter Naeher

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Mark A Daniels

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Pia P Yachi

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Barbara Hausmann

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Immanuel F Luescher

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Ed Palmer

8

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Europe PubMed Central

PMC publication ID

20 August 2017

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publication date

1 June 2008

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Europe PubMed Central

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20 August 2017

Journal of Immunology

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Europe PubMed Central

PMC publication ID

20 August 2017

180

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Europe PubMed Central

PMC publication ID

20 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

8211-8221

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2764738/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

A constant affinity threshold for T cell tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Using live FRET imaging to reveal early protein-protein interactions during T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Photobleaching-corrected FRET efficiency imaging of live cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

CD3 delta establishes a functional link between the T cell receptor and CD8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Rare, structurally homologous self-peptides promote thymocyte positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

ITAM multiplicity and thymocyte selection: how low can you go?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

CD8 lineage commitment in the absence of CD8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Mechanism of activation for Zap-70 catalytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

T cell receptor antagonist peptides induce positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

CD4 and CD8 molecules can physically associate with the same T-cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

CD8 is needed for development of cytotoxic T cells but not helper T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Profound block in thymocyte development in mice lacking p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

6 September 2017

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

14 September 2017

Altered peptide ligands induce delayed CD8-T cell receptor interaction--a role for CD8 in distinguishing antigen quality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

14 September 2017

A role for the alpha-chain connecting peptide motif in mediating TCR-CD8 cooperation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

28 September 2017

A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

28 September 2017

T-cell-receptor affinity and thymocyte positive selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

28 September 2017

T cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

26 June 2018

CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

26 June 2018

A motif within the T cell receptor alpha chain constant region connecting peptide domain controls antigen responsiveness.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

26 June 2018

Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

26 June 2018

Empty MHC class I molecules come out in the cold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

26 June 2018

A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

26 June 2018

Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

26 June 2018

Kinetics of MHC-CD8 interaction at the T cell membrane.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

2 September 2018

Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

2 September 2018

Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

2 September 2018

Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

2 September 2018

Positive selection through a motif in the alphabeta T cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

2 September 2018

The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

2 September 2018

Characterization of the ovalbumin-specific TCR transgenic line OT-I: MHC elements for positive and negative selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

3 December 2018

Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

3 December 2018

Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α-mRNA of BW5147 origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2764738

3 December 2018

Photoaffinity labeling of the T cell receptor on cloned cytotoxic T lymphocytes by covalent photoreactive ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An analysis of sequence variation in the beta chain framework and complementarity determining regions of an allo-reactive T cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18523287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.180.12.8211

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Europe PubMed Central

PMC publication ID

20 August 2017

release_2yltie3r2ncljonrpyorsl4d6a

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https://api.fatcat.wiki/v0/release/2yltie3r2ncljonrpyorsl4d6a

24 November 2022

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PMC publication ID

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Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

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Europe PubMed Central

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20 August 2017

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