(Q37395726)

20 August 2017

Discovery of novel Myc-Max heterodimer disruptors with a three-dimensional pharmacophore model (English)

1 reference

20 August 2017

8

Ivet Bahar

0 references

John S. Lazo

7

object named as

John S Lazo

1 reference

20 August 2017

Gabriela Mustata

1

1 reference

20 August 2017

Ariele Viacava Follis

2

1 reference

20 August 2017

Dalia I Hammoudeh

3

1 reference

20 August 2017

Steven J Metallo

4

1 reference

20 August 2017

Huabo Wang

5

1 reference

20 August 2017

Edward V Prochownik

6

1 reference

20 August 2017

language of work or name

English

0 references

publication date

1 March 2009

1 reference

Journal of Medicinal Chemistry

20 August 2017

1 reference

20 August 2017

52

1 reference

20 August 2017

5

1 reference

20 August 2017

1247-1250

1 reference

Modelling Myc inhibition as a cancer therapy

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Intrinsically Disordered Proteins in Human Diseases: Introducing the D 2 Concept

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Improved low molecular weight Myc-Max inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Anticancer medicines in development: assessment of bioactivity profiles within the National Cancer Institute anticancer screening data

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Evaluating chemical structure similarity as an indicator of cellular growth inhibition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

ZINC--a free database of commercially available compounds for virtual screening

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

c-Myc as a therapeutic target in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Fragmental Methods in the Analysis of Biological Activities of Diverse Compound Sets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Do structurally similar molecules have similar biological activity?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

The human CYP3A subfamily: practical considerations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

C-Myc-independent restoration of multiple phenotypes by two C-Myc target genes with overlapping functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Low molecular weight inhibitors of Myc-Max interaction and function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Differential apoptotic behaviors of c-myc, N-myc, and L-myc oncoproteins.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Using a staged multi-objective optimization approach to find selective pharmacophore models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

GALAHAD: 1. pharmacophore identification by hypermolecular alignment of ligands in 3D.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

A marriage made in torsional space: using GALAHAD models to drive pharmacophore multiplet searches.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Oncogenic activity of the c-Myc protein requires dimerization with Max.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765518

Integrating Myc and TGF-beta signalling in cell-cycle control

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19215087

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM801278G

1 reference

20 August 2017

1 reference

20 August 2017

1 reference