(Q37401084)

20 August 2017

1 reference

title

Key role of macrophages in the pathogenesis of CD18 hypomorphic murine model of psoriasis (English)

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Karin Scharffetter-Kochanek

20 August 2017

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series ordinal

4

object named as

Karin Scharffetter-Kochanek

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20 August 2017

Honglin Wang

1

1 reference

20 August 2017

Thorsten Peters

series ordinal

2

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20 August 2017

Anca Sindrilaru

series ordinal

3

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20 August 2017

language of work or name

English

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publication date

26 February 2009

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Journal of Investigative Dermatology

20 August 2017

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20 August 2017

129

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20 August 2017

5

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20 August 2017

1100-1114

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https://scigraph.springernature.com/pub.10.1038/jid.2009.43

20 August 2017

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Signalling pathways of the TNF superfamily: a double-edged sword

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Monocyte chemoattractant protein-1 accelerates atherosclerosis in apolipoprotein E-deficient mice

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7 January 2021

Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior

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7 January 2021

Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling

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7 January 2021

Development of dermatitis in CD18-deficient PL/J mice is not dependent on bacterial flora, and requires both CD4+ and CD8+ T lymphocytes

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7 January 2021

Signal transduction by tumor necrosis factor and its relatives

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7 January 2021

Interleukin 20: discovery, receptor identification, and role in epidermal function

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7 January 2021

Novel protective effects of stem cell factor in a murine model of acute septic peritonitis. Dependence on MCP-1

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7 January 2021

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

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7 January 2021

A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice

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7 January 2021

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial

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7 January 2021

TNF-R1 signaling: a beautiful pathway

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7 January 2021

Successful treatment of severe psoriasis and psoriatic arthritis with adalimumab.

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7 January 2021

Misbehaving macrophages in the pathogenesis of psoriasis

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Immunohistochemical identification of type II alternatively activated dendritic macrophages (RM 3/1+3, MS-1+/-, 25F9-) in psoriatic dermis

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Hormone regulation of microglial cell activation: relevance to multiple sclerosis

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7 January 2021

Critical protective role of mast cells in a model of acute septic peritonitis

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7 January 2021

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions

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7 January 2021

The macrophage scavenger receptor CD163.

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7 January 2021

Development and maturation of secondary lymphoid tissues.

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The Association of CD18 Alleles with Anti-myeloperoxidase Subtypes of ANCA-Associated Systemic Vasculitides

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The tumour necrosis factor-alpha inhibitor adalimumab rapidly reverses the decrease in epidermal Langerhans cell density in psoriatic plaques.

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

https://api.crossref.org/works/10.1038%2FJID.2009.43

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7 January 2021

MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Etanercept for the treatment of psoriasis and psoriatic arthritis

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Expression of HLA-DR molecules by keratinocytes, and presence of Langerhans cells in the dermal infiltrate of active psoriatic plaques

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Pharmacodynamic and pharmacokinetic response to anti-tumor necrosis factor-alpha monoclonal antibody (infliximab) treatment of moderate to severe psoriasis vulgaris

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

A randomized trial of etanercept as monotherapy for psoriasis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Mouse models of psoriasis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Increased macrophage activation mediated through toll-like receptors in rheumatoid arthritis

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Integrins: a family of cell surface receptors

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https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Identification of susceptibility loci for skin disease in a murine psoriasis model

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Localization of tumour necrosis factor-alpha (TNF-alpha) and its receptors in normal and psoriatic skin: epidermal cells express the 55-kD but not the 75-kD TNF receptor

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The immunologic basis for the treatment of psoriasis with new biologic agents

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Markers of mouse macrophage development detected by monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The TNF and TNF receptor superfamilies: integrating mammalian biology

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Targeting TNFalpha rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Adenoviral-mediated overexpression of monocyte chemoattractant protein-1 differentially alters the development of Th1 and Th2 type responses in vivo

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Adalimumab for the treatment of patients with moderately to severely active psoriatic arthritis: results of a double-blind, randomized, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Novel SNPs in the CD18 gene validate the association with MPO-ANCA+ vasculitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Anti-CD4 monoclonal antibody therapy in severe psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Deepening our understanding of immune sentinels in the skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Characterization of lymphocyte-dependent angiogenesis using a SCID mouse: human skin model of psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Anti-TNF-alpha therapies: the next generation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Interleukin-10 and related cytokines and receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Biological functions of tumor necrosis factor cytokines and their receptors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The role of perivascular and meningeal macrophages in experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Crosstalk between Keratinocytes and Adaptive Immune Cells in an IκBα Protein-Mediated Inflammatory Disease of the Skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Epidermal overexpression of interleukin-19 and -20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine a or calcipotriol.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: correlation with the development of diabetes

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

T cells involved in psoriasis vulgaris belong to the Th1 subset

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-alpha levels

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Recognition of CpG DNA is mediated by signaling pathways dependent on the adaptor protein MyD88

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

https://api.crossref.org/works/10.1038%2FJID.2009.43

1 reference

7 January 2021

Murine psoriasis-like disorder induced by naive CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

https://api.crossref.org/works/10.1038%2FJID.2009.43

1 reference

7 January 2021

Differential effects of interleukin 12 and interleukin 10 on superantigen-induced expression of cutaneous lymphocyte-associated antigen (CLA) and alphaEbeta7 integrin (CD103) by CD8+ T cells.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Interleukin-20 as a target in psoriasis treatment

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Regulation of T-cell activation in the lung: alveolar macrophages induce reversible T-cell anergy in vitro associated with inhibition of interleukin-2 receptor signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The role of alveolar macrophages in regulation of lung inflammation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical study

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Resolution of cutaneous inflammation after local elimination of macrophages

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Identification of factor XIII-A as a marker of alternative macrophage activation.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Skin manifestations in congenital deficiency of leucocyte-adherence glycoproteins (CDLG)

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Epithelium-lining macrophages in psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Local removal of phagocytic synovial lining cells by clodronate-liposomes decreases cartilage destruction during collagen type II arthritis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

The CD11b/CD18-integrin in the pathogenesis of psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Depletion of synovial macrophages in rheumatoid arthritis by an anti-FcgammaRI-calicheamicin immunoconjugate

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Depletion of folate-receptor-positive macrophages leads to alleviation of symptoms and prolonged survival in two murine models of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Expression of CCR2 on monocytes and macrophages in chronically inflamed skin in atopic dermatitis and psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Organization of the monocyte/macrophage system of normal human skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Cutting edge: immune cells as sources and targets of the IL-10 family members?

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Dermal injection of immunocytes induces psoriasis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Unraveling the pros and cons of interferon-gamma gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

1 reference

https://api.crossref.org/works/10.1038%2FJID.2009.43

7 January 2021

Identifiers

DOI

10.1038/JID.2009.43

1 reference

20 August 2017

1 reference