(Q37401396)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

review article

1 reference

title

Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

George S Baillie

series ordinal

1

1 reference

20 August 2017

language of work or name

English

0 references

publication date

23 February 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

276

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

1790-1799

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19243430%20AND%20SRC:MED&resulttype=core&format=json

Cyclic nucleotide research -- still expanding after half a century

22 January 2020

cites work

1 reference

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21 January 2018

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21 January 2018

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Immunohistochemical localization of 3′:5′-cyclic AMP and 3′:5′-cyclic GMP in rat renal cortex: Effect of parathyroid hormone

21 January 2018

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21 January 2018

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Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

21 January 2018

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Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering

21 January 2018

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Novel single chain cAMP sensors for receptor-induced signal propagation.

21 January 2018

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21 January 2018

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Review article: cyclic AMP sensors in living cells: what signals can they actually measure?

21 January 2018

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A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell

21 January 2018

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Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.

21 January 2018

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Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion

21 January 2018

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cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling

21 January 2018

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Localized effects of cAMP mediated by distinct routes of protein kinase A.

21 January 2018

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Epac proteins: multi-purpose cAMP targets

21 January 2018

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Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

21 January 2018

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Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

21 January 2018

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A specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes.

21 January 2018

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Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis

21 January 2018

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Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway

21 January 2018

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Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases

21 January 2018

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PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases

21 January 2018

1 reference

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Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

21 January 2018

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Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases.

21 January 2018

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In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

21 January 2018

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Real-time monitoring of phosphodiesterase inhibition in intact cells.

21 January 2018

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Compartmentation of cAMP signaling in cardiac myocytes: a computational study

21 January 2018

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Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness

21 January 2018

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Keynote review: phosphodiesterase-4 as a therapeutic target

21 January 2018

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PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

21 January 2018

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Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum

21 January 2018

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Chimeric constructs show that the unique N-terminal domain of the cyclic AMP phosphodiesterase RD1 (RNPDE4A1A; rPDE-IVA1) can confer membrane association upon the normally cytosolic protein chloramphenicol acetyltransferase

21 January 2018

1 reference

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TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid

21 January 2018

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The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins

21 January 2018

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Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays

21 January 2018

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Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

21 January 2018

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beta-arrestins: traffic cops of cell signaling

21 January 2018

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beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi

21 January 2018

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RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.

21 January 2018

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Dynamic regulation, desensitization, and cross-talk in discrete subcellular microdomains during beta2-adrenoceptor and prostanoid receptor cAMP signaling

21 January 2018

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Critical role of PDE4D in beta2-adrenoceptor-dependent cAMP signaling in mouse embryonic fibroblasts

21 January 2018

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1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1

21 January 2018

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TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling

21 January 2018

1 reference

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Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

21 January 2018

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Scaffold proteins of MAP-kinase modules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

AKAP signaling complexes: getting to the heart of the matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.06926.X