(Q37424084)

English

Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway

scientific article published on 05 December 2013

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scholarly article

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Europe PubMed Central

20 August 2017

Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway (English)

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20 August 2017

apoptotic process

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based on heuristic

inferred from title

7

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10 June 2020

author name string

C Lv

1

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10 June 2020

Y Hong

2

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10 June 2020

L Miao

3

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10 June 2020

C Li

4

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10 June 2020

G Xu

5

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10 June 2020

S Wei

6

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10 June 2020

C Huang

8

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10 June 2020

B Jiao

9

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10 June 2020

publication date

5 December 2013

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Cell Death and Disease

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10 June 2020

4

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10 June 2020

e952

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10 June 2020

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

1 December 2013

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April 2022 Public Data File from Crossref

copyright status

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Wentilactone B induces G2/M phase arrest and apoptosis via the Ras/Raf/MAPK signaling pathway in human hepatoma SMMC-7721 cells

1 reference

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1 reference

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23 August 2017

Asperolide A, a marine-derived tetranorditerpenoid, induces G2/M arrest in human NCI-H460 lung carcinoma cells, is mediated by p53-p21 stabilization and modulated by Ras/Raf/MEK/ERK signaling pathway.

1 reference

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The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy

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1 reference

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1 reference

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1 reference

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DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

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1 reference

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Mitochondrial reactive oxygen species in cell death signaling

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MAPK signal pathways in the regulation of cell proliferation in mammalian cells

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1 reference

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Regulation of the p53 tumor suppressor protein

1 reference

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Redox regulation of cellular signalling

1 reference

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48.

1 reference

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1 reference

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12 December 2020

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10.1038/CDDIS.2013.484

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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