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English
Conformational changes and protein stability of the pro-apoptotic protein Bax.
scientific article published on February 2009
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
title
Conformational changes and protein stability of the pro-apoptotic protein Bax
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
main subject
apoptotic process
0 references
author
Stephanie Bleicken
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
author name string
Kornelius Zeth
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
publication date
1 February 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
published in
Journal of Bioenergetics and Biomembranes
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
volume
41
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
page(s)
29-40
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
exact match
https://scigraph.springernature.com/pub.10.1007/s10863-009-9202-1
0 references
cites work
Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax
1 reference
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PubMed Central
reference URL
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23 August 2017
How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities
1 reference
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PubMed Central
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23 August 2017
Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Probing protein folding and conformational transitions with fluorescence.
1 reference
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PubMed Central
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23 August 2017
Oxygen profiles in membranes.
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PubMed Central
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23 August 2017
The multidomain proapoptotic molecules Bax and Bak are directly activated by heat
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Mitochondrial fission in apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Structural biology of the Bcl-2 family of proteins
1 reference
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PubMed Central
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23 August 2017
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Bcl-2-family proteins and the role of mitochondria in apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Humanin peptide suppresses apoptosis by interfering with Bax activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
p53 has a direct apoptogenic role at the mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
The N-terminal end of Bax contains a mitochondrial-targeting signal.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
The Bcl2 family: regulators of the cellular life-or-death switch
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Structure of Bax: coregulation of dimer formation and intracellular localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
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23 August 2017
Conformation of the Bax C-terminus regulates subcellular location and cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Regulated targeting of BAX to mitochondria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Movement of Bax from the cytosol to mitochondria during apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
A simple method for displaying the hydropathic character of a protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
23 August 2017
Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
14 September 2017
Oxygen permeation profile in lipid membranes: comparison with transmembrane polarity profile
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
14 September 2017
Quantitative analysis of protein far UV circular dichroism spectra by neural networks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
26 June 2018
Size and shape of detergent micelles determined by small-angle X-ray scattering
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
2 September 2018
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
2 September 2018
N-terminal cleavage of bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes bcl-2-independent cytochrome C release and apoptotic cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
2 September 2018
Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2778690
retrieved
3 December 2018
Conformational change of Bax: a question of life or death
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19255832
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Calpain-1 Regulates Bax and Subsequent Smac-dependent Caspase-3 Activation in Neutrophil Apoptosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19255832
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Membrane-insertion fragments of Bcl-xL, Bax, and Bid
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19255832
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nonionic detergents induce dimerization among members of the Bcl-2 family
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19255832
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S10863-009-9202-1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
PMC publication ID
2778690
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
PubMed publication ID
19255832
1 reference
stated in
Europe PubMed Central
PMC publication ID
2778690
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19255832%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 January 2020
ResearchGate publication ID
24172185
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