(Q37426582)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

6

1 reference

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10 February 2020

author name string

Shahid M Nimjee

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Sabah Oney

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Zoya Volovyk

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Kristin M Bompiani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Steve B Long

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Bruce A Sullenger

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

language of work or name

English

0 references

publication date

21 October 2009

1 reference

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10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

page(s)

2105-2111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

Crystal structure of an RNA aptamer bound to thrombin

10 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Molecular assembly for high-performance bivalent nucleic acid inhibitor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Aptamers: an emerging class of therapeutics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

New anticoagulant therapy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Role of antiplatelet therapy in cardiovascular disease I: Acute coronary syndromes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Generation of species cross-reactive aptamers using "toggle" SELEX.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Binding of thrombin to glycoprotein Ib accelerates the hydrolysis of Par-1 on intact platelets

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Effect of oligodeoxynucleotide thrombin aptamer on thrombin inhibition by heparin cofactor II and antithrombin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Thrombin signalling and protease-activated receptors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Pilot study of the efficacy of a thrombin inhibitor for use during cardiopulmonary bypass

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

A rapid method to isolate platelets from human blood by density gradient centrifugation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

RNA aptamer to thrombin binds anion-binding exosite-2 and alters protease inhibition by heparin-binding serpins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Evidence that both exosites on thrombin participate in its high affinity interaction with fibrin

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Association of gammaA/gamma' fibrinogen levels and coronary artery disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Structural and functional mapping of the thrombin domain involved in the binding to the platelet glycoprotein Ib.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779679

Multidomain targeting generates a high-affinity thrombin-inhibiting bivalent aptamer

3 December 2018

1 reference

12 December 2020

An Ambiguous Structure of a DNA 15-mer Thrombin Complex

1 reference

12 December 2020

Antidote-mediated control of an anticoagulant aptamer in vivo

1 reference

12 December 2020

Platelet glycoprotein Ib alpha binds to thrombin anion-binding exosite II inducing allosteric changes in the activity of thrombin.

1 reference

12 December 2020

In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits

1 reference

12 December 2020

Evidence for allosteric linkage between exosites 1 and 2 of thrombin

1 reference

12 December 2020

Exosites 1 and 2 are essential for protection of fibrin-bound thrombin from heparin-catalyzed inhibition by antithrombin and heparin cofactor II

1 reference

12 December 2020

Identifiers

DOI

10.1261/RNA.1240109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19846574%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

19846574

1 reference