Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24652403)
Watch
English
Crystal structure of an RNA aptamer bound to thrombin
scientific article
In more languages
edit
Statements
instance of
scholarly article
0 references
title
Crystal structure of an RNA aptamer bound to thrombin
(English)
0 references
main subject
crystal structure
0 references
author name string
Stephen B Long
series ordinal
1
0 references
Meredith B Long
series ordinal
2
0 references
Rebekah R White
series ordinal
3
0 references
Bruce A Sullenger
series ordinal
4
0 references
language of work or name
English
0 references
publication date
December 2008
0 references
published in
RNA
0 references
volume
14
0 references
page(s)
2504-12
0 references
issue
12
0 references
cites work
RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Crystal structure of NF- B (p50)2 complexed to a high-affinity RNA aptamer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Encapsulating streptomycin within a small 40-mer RNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Refinement of the solution structure of the heparin-binding domain of vascular endothelial growth factor using residual dipolar couplings
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
The structural basis for molecular recognition by the vitamin B 12 RNA aptamer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
The CCP4 suite: programs for protein crystallography
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Shape complementarity at protein/protein interfaces
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Improved methods for building protein models in electron density maps and the location of errors in these models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
In vitro selection of RNA molecules that bind specific ligands
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
A cell-based model of hemostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Ribbons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
The penultimate rotamer library
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
7 April 2017
Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Serpins in thrombosis, hemostasis and fibrinolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Aptamers: an emerging class of therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Vascular endothelial growth factor: basic science and clinical progress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Molecular mimicry of the NF-kappaB DNA target site by a selected RNA aptamer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Thrombin interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
RNA aptamers as reversible antagonists of coagulation factor IXa.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Generation of species cross-reactive aptamers using "toggle" SELEX.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Shape and electrostatic complementarity at viral antigen-antibody complexes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Adaptive recognition by nucleic acid aptamers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Oligonucleotide NX1838 inhibits VEGF165-mediated cellular responses in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Selection and characterization of an RNA decoy for transcription factor NF-kappa B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Visualizing and quantifying molecular goodness-of-fit: small-probe contact dots with explicit hydrogen atoms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Inhibitory DNA ligands to platelet-derived growth factor B-chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
The clot thickens: clues provided by thrombin structure.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
High-affinity RNA ligands to human alpha-thrombin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Nucleoside conformation is determined by the electronegativity of the sugar substituent.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Quantitative characterization of the thrombin-heparin interaction. Discrimination between specific and nonspecific binding models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
Selection of single-stranded DNA molecules that bind and inhibit human thrombin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 September 2017
The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
30 May 2018
Isolation of RNA aptamers specific to the NS3 protein of hepatitis C virus from a pool of completely random RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
30 May 2018
Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
30 May 2018
Protein-RNA interactions: exploring binding patterns with a three-dimensional superposition analysis of high resolution structures.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 November 2018
Crystal structure of thrombin bound to heparin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 November 2018
RNA aptamer to thrombin binds anion-binding exosite-2 and alters protease inhibition by heparin-binding serpins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590953
retrieved
28 November 2018
An Ambiguous Structure of a DNA 15-mer Thrombin Complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18971322
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18971322
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Processing of X-ray diffraction data collected in oscillation mode
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18971322
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1261/RNA.1239308
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3863221
OpenCitations bibliographic resource ID
3863221
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3863221
PMCID
2590953
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3863221
PubMed ID
18971322
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3863221
ResearchGate publication ID
23438947
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
