(Q34341165)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15311269%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin (English)

1 reference

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31 December 2019

1

1 reference

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31 December 2019

author name string

Daniel J D Johnson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15311269%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Charles T Esmon

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15311269%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

James A Huntington

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15311269%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

publication date

15 August 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15311269%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

31 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15311269%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

11

1 reference

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31 December 2019

issue

9

1 reference

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31 December 2019

page(s)

857-862

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15311269%20AND%20SRC:MED&resulttype=core&format=json

A player of many parts: the spotlight falls on thrombin's structure.

31 December 2019

cites work

1 reference

The clot thickens: clues provided by thrombin structure.

21 January 2018

1 reference

Mechanisms of glycosaminoglycan activation of the serpins in hemostasis

21 January 2018

1 reference

Targeted gene disruption of natural anticoagulant proteins in mice

21 January 2018

1 reference

Order out of complexity--protein structures that interact with heparin

21 January 2018

1 reference

The antithrombin-binding sequence of heparin

21 January 2018

1 reference

The structure of heparin oligosaccharide fragments with high anti-(factor Xa) activity containing the minimal antithrombin III-binding sequence Chemical and13C nuclear-magnetic-resonance studies

21 January 2018

1 reference

Heparin, antithrombin, and abnormal clotting

21 January 2018

1 reference

Heparin activates antithrombin anticoagulant function by generating new interaction sites (exosites) for blood clotting proteinases.

21 January 2018

1 reference

An update on heparins at the beginning of the new millennium

21 January 2018

1 reference

Anti-thrombin activities of heparin. Effect of saccharide chain length on thrombin inhibition by heparin cofactor II and by antithrombin

21 January 2018

1 reference

Heparin-induced thrombocytopenia: an overview

21 January 2018

1 reference

Synthesis of thrombin-inhibiting heparin mimetics without side effects

21 January 2018

1 reference

Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases

21 January 2018

1 reference

The structure of a Michaelis serpin-protease complex

21 January 2018

1 reference

Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism

21 January 2018

1 reference

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

The anticoagulant activation of antithrombin by heparin

21 January 2018

1 reference

Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin

21 January 2018

1 reference

The molecular environment of the Na+ binding site of thrombin

21 January 2018

1 reference

Molecular mapping of the heparin-binding exosite of thrombin

21 January 2018

1 reference

Functional requirements for inhibition of thrombin by antithrombin III in the presence and absence of heparin

21 January 2018

1 reference

Protein engineering thrombin for optimal specificity and potency of anticoagulant activity in vivo

21 January 2018

1 reference

Localization of an Antithrombin Exosite That Promotes Rapid Inhibition of Factors Xa and IXa Dependent on Heparin Activation of the Serpin

21 January 2018

1 reference

The ternary complex of antithrombin-anhydrothrombin-heparin reveals the basis of inhibitor specificity

21 January 2018

1 reference

The Influence of Hinge Region Residue Glu-381 on Antithrombin Allostery and Metastability

21 January 2018

1 reference

An approach to multi-copy search in molecular replacement

21 January 2018

1 reference

PRODRG, a program for generating molecular topologies and unique molecular descriptors from coordinates of small molecules.

21 January 2018

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

21 January 2018

1 reference

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

Crystal structure of antithrombin in a heparin-bound intermediate state

21 January 2018

1 reference

Influence of Arginines 93, 97, and 101 of thrombin to its functional specificity

21 January 2018

1 reference

Rational engineering of activity and specificity in a serine protease

31 March 2020

1 reference

The Na+ binding site of thrombin

31 March 2020

1 reference

Identification of thrombin residues that modulate its interactions with antithrombin III and alpha 1-antitrypsin

31 March 2020

1 reference

https://api.fatcat.wiki/v0/release/jsl4khntfneevpkivnp56kckrq

31 March 2020

Identifiers

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30 July 2022

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Fatcat ID

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https://api.fatcat.wiki/v0/release/jsl4khntfneevpkivnp56kckrq

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30 July 2022

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1 reference