(Q37432488)

English

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity

scientific article published on 23 September 2009

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity (English)

1 reference

Europe PubMed Central

20 August 2017

0 references

1 reference

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inferred from title

Holly Van Remmen

11

object named as

Holly Van Remmen

1 reference

Europe PubMed Central

20 August 2017

Arlan G. Richardson

10

object named as

Arlan Richardson

1 reference

Europe PubMed Central

20 August 2017

author name string

Yiqiang Zhang

1

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Europe PubMed Central

20 August 2017

Yuji Ikeno

2

1 reference

Europe PubMed Central

20 August 2017

Wenbo Qi

3

1 reference

Europe PubMed Central

20 August 2017

Asish Chaudhuri

4

1 reference

Europe PubMed Central

20 August 2017

Yan Li

5

1 reference

Europe PubMed Central

20 August 2017

Alex Bokov

6

1 reference

Europe PubMed Central

20 August 2017

Suzanne R Thorpe

7

1 reference

Europe PubMed Central

20 August 2017

John W Baynes

8

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Europe PubMed Central

20 August 2017

Charles Epstein

9

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Europe PubMed Central

20 August 2017

language of work or name

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publication date

23 September 2009

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Europe PubMed Central

20 August 2017

The Journals of Gerontology

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Europe PubMed Central

20 August 2017

64

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Europe PubMed Central

20 August 2017

12

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Europe PubMed Central

20 August 2017

1212-1220

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Europe PubMed Central

20 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2781787/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Overexpression of Mn superoxide dismutase does not increase life span in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Biological approaches to mechanistically understand the healthy life span extension achieved by calorie restriction and modulation of hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

The overexpression of major antioxidant enzymes does not extend the lifespan of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Role of hormesis in life extension by caloric restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

The in vivo gene expression signature of oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Stress-response hormesis and aging: "that which does not kill us makes us stronger".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Hormesis in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Trends in oxidative aging theories

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Glutathione-peroxidase-1 null muscle progenitor cells are globally defective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Toward a unified theory of caloric restriction and longevity regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Extension of murine life span by overexpression of catalase targeted to mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Aging: a theory based on free radical and radiation chemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Low glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

The use of transgenic and mutant mice to study oxygen free radical metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Oxygen-induced mitochondrial damage and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

23 August 2017

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

26 June 2018

Thioredoxin-2 affects lifespan and oxidative stress in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

Peroxiredoxin 6 gene-targeted mice show increased lung injury with paraquat-induced oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

N epsilon-(carboxymethyl)lysine (CML) as a biomarker of oxidative stress in long-lived tissue proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

In vivo antioxidant role of glutathione peroxidase: evidence from knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

Overexpression of glutathione reductase extends survival in transgenic Drosophila melanogaster under hyperoxia but not normoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

Edema formation exacerbates neurological and histological outcomes after focal cerebral ischemia in CuZn-superoxide dismutase gene knockout mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781787

2 September 2018

Statistical methods for testing effects on “maximum lifespan”

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2FGLP132

21 January 2018

Housing density does not influence the longevity effect of calorie restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible effects of long-term caloric restriction on protein oxidative damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in rate of occurrence of age related lesions in dietary restricted laboratory mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/GERONA/GLP132

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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