(Q37447788)

English

iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.

scientific article published on 02 September 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19726666%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase (English)

1 reference

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6 February 2020

1 reference

Hyphessobrycon rosaceus

1 reference

Streptomyces platensis

1 reference

Streptomyces coelicolor

1 reference

Streptomyces albus

1 reference

Streptomyces lividans

1 reference

Streptomyces albidoflavus

1 reference

Streptomyces avermitilis

1 reference

Iso-migrastatin

1 reference

4-[(5S)-5-[(3Z,5R,6S,7S,8E,12E)-6-hydroxy-7-methoxy-3,5-dimethyl-14-oxo-1-oxacyclotetradeca-3,8,12-trien-2-yl]-4-oxohexyl]piperidine-2,6-dione

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1 reference

1 reference

9

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6 February 2020

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Si-Kyu Lim

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6 February 2020

Jianhua Ju

2

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6 February 2020

Emmanuel Zazopoulos

3

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6 February 2020

Hui Jiang

4

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6 February 2020

Jeong-Woo Seo

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6 February 2020

Yihua Chen

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6 February 2020

Zhiyang Feng

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6 February 2020

Scott R Rajski

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6 February 2020

Ben Shen

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6 February 2020

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2 September 2009

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6 February 2020

full work available at URL

http://www.jbc.org/article/S0021925820381874/pdf

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19 March 2024

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Journal of Biological Chemistry

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6 February 2020

284

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6 February 2020

43

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6 February 2020

29746-29756

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6 February 2020

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Type I polyketide synthases that require discrete acyltransferases

1 reference

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1 reference

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23 August 2017

Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.

1 reference

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Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds

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Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

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Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE

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Migrastatin and a new compound, isomigrastatin, from Streptomyces platensis

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Polyketide biosynthesis: a millennium review

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Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities

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1 reference

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10.1074/JBC.M109.046805

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6 February 2020

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Europe PubMed Central

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6 February 2020

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Europe PubMed Central

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6 February 2020

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