(Q37452434)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

esophageal squamous cell carcinoma

25 March 2020

main subject

1 reference

1 reference

squamous cell carcinoma

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Anand Mayakonda

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Benjamin P Berman

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Phillip Koeffler

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

author name string

Jia-Jie Hao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

De-Chen Lin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Yan-Yi Jiang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Chen Chang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Ye Jiang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Chen-Chen Lu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Zhi-Zhou Shi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Xin Xu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Yu Zhang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Yan Cai

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Jin-Wu Wang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Qi-Min Zhan

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Wen-Qiang Wei

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Ming-Rong Wang

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

language of work or name

English

0 references

publication date

17 October 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

volume

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

page(s)

1500-1507

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ng.3683

25 March 2020

exact match

0 references

cites work

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1 reference

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DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution

23 August 2017

1 reference

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Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma

23 August 2017

1 reference

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Multiple region whole-exome sequencing reveals dramatically evolving intratumor genomic heterogeneity in esophageal squamous cell carcinoma

23 August 2017

1 reference

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The Molecular Taxonomy of Primary Prostate Cancer

23 August 2017

1 reference

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DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors

23 August 2017

1 reference

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The tumor area occupied by Tbet+ cells in deeply invading cervical cancer predicts clinical outcome

23 August 2017

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Whole-transcriptome analysis of flow-sorted cervical cancer samples reveals that B cell expressed TCL1A is correlated with improved survival.

23 August 2017

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Paired exome analysis of Barrett's esophagus and adenocarcinoma

23 August 2017

1 reference

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Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

23 August 2017

1 reference

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Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

23 August 2017

1 reference

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Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma

23 August 2017

1 reference

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The role of DNA methylation in directing the functional organization of the cancer epigenome

23 August 2017

1 reference

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Integrative analysis of 111 reference human epigenomes

23 August 2017

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Global cancer statistics, 2012

23 August 2017

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Biological and therapeutic impact of intratumor heterogeneity in cancer evolution

23 August 2017

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From FastQ data to high confidence variant calls: the Genome Analysis Toolkit best practices pipeline

23 August 2017

1 reference

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ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

23 August 2017

1 reference

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Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

23 August 2017

1 reference

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Genetic landscape of esophageal squamous cell carcinoma

23 August 2017

1 reference

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Comprehensive molecular characterization of gastric adenocarcinoma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

SAMBLASTER: fast duplicate marking and structural variant read extraction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Genomic and molecular characterization of esophageal squamous cell carcinoma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Identification of genomic alterations in oesophageal squamous cell cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Genome-wide gene expression profile analyses identify CTTN as a potential prognostic marker in esophageal cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Discovery and saturation analysis of cancer genes across 21 tumour types

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

A reference methylome database and analysis pipeline to facilitate integrative and comparative epigenomics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Estimation of the fraction of cancer cells in a tumor DNA sample using DNA methylation

23 August 2017

1 reference

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Pan-cancer patterns of somatic copy number alteration

23 August 2017

1 reference

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Signatures of mutational processes in human cancer

23 August 2017

1 reference

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PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Low-level processing of Illumina Infinium DNA Methylation BeadArrays

23 August 2017

1 reference

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Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

23 August 2017

1 reference

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Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

23 August 2017

1 reference

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Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

23 August 2017

1 reference

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Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Absolute quantification of somatic DNA alterations in human cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Epigenomic program of Barrett's-associated neoplastic progression reveals possible involvement of insulin signaling pathways

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Temporal dissection of tumorigenesis in primary cancers

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

A decade of exploring the cancer epigenome - biological and translational implications

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

A method and server for predicting damaging missense mutations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Redefining CpG islands using hidden Markov models

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

The Sequence Alignment/Map format and SAMtools

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Circular binary segmentation for the analysis of array-based DNA copy number data

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

A census of human cancer genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Fast and accurate phylogeny reconstruction algorithms based on the minimum-evolution principle

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Kinase inhibitors and monoclonal antibodies in oncology: clinical implications

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Cancer: evolution within a lifetime

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Epigenetic alterations and their clinical implications in esophageal squamous cell carcinoma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

DNA methylation dynamics in health and disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

A novel wnt regulatory axis in endometrioid endometrial cancer.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Consistent and differential genetic aberrations between esophageal dysplasia and squamous cell carcinoma detected by array comparative genomic hybridization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Cancer statistics in China, 2015.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Downregulation of EphA7 by hypermethylation in colorectal cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Predicting functional effect of human missense mutations using PolyPhen-2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Intratumor heterogeneity: seeing the wood for the trees.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5127772

Infiltration of Lynch Colorectal Cancers by Activated Immune Cells Associates with Early Staging of the Primary Tumor and Absence of Lymph Node Metastases

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27749841

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protocadherin 10 suppresses tumorigenesis and metastasis in colorectal cancer and its genetic loss predicts adverse prognosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27749841

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Do short, frequent DNA sequence motifs mould the epigenome?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27749841

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.3683

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27749841%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

PubMed publication ID

27749841

1 reference