(Q37456300)

English

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Treatment With Sirukumab (CNTO 136) in Patients With Active Lupus Nephritis

scientific article published on 25 April 2016

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Treatment With Sirukumab (CNTO 136) in Patients With Active Lupus Nephritis (English)

1 reference

Europe PubMed Central

20 August 2017

0 references

multicenter clinical trial

0 references

Ronald van Vollenhoven

2

object named as

Ronald F van Vollenhoven

0 references

3

object named as

Cynthia Aranow

1 reference

Europe PubMed Central

20 August 2017

1

object named as

Brad H Rovin

1 reference

Europe PubMed Central

20 August 2017

author name string

Carrie Wagner

4

1 reference

Europe PubMed Central

20 August 2017

Robert Gordon

5

1 reference

Europe PubMed Central

20 August 2017

Yanli Zhuang

6

1 reference

Europe PubMed Central

20 August 2017

Stanley Belkowski

7

1 reference

Europe PubMed Central

20 August 2017

Benjamin Hsu

8

1 reference

Europe PubMed Central

20 August 2017

publication date

25 April 2016

1 reference

Europe PubMed Central

20 August 2017

Arthritis & Rheumatology

1 reference

Europe PubMed Central

20 August 2017

68

1 reference

Europe PubMed Central

20 August 2017

2174-2183

1 reference

Europe PubMed Central

20 August 2017

9

1 reference

Europe PubMed Central

20 August 2017

Lupus nephritis: from pathogenesis to targets for biologic treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Sirukumab, a human anti-interleukin-6 monoclonal antibody: a randomised, 2-part (proof-of-concept and dose-finding), phase II study in patients with active rheumatoid arthritis despite methotrexate therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Lupus nephritis: the evolving role of novel therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Phase I, randomized, double-blind, placebo-controlled, multiple intravenous, dose-ascending study of sirukumab in cutaneous or systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Pharmacokinetics, pharmacodynamics and safety of a human anti-IL-6 monoclonal antibody (sirukumab) in healthy subjects in a first-in-human study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

A prospective study of protein excretion using short-interval timed urine collections in patients with lupus nephritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

The classification of glomerulonephritis in systemic lupus erythematosus revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Morbidity and mortality in systemic lupus erythematosus during a 5-year period. A multicenter prospective study of 1,000 patients. European Working Party on Systemic Lupus Erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

The 1982 revised criteria for the classification of systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Interleukin-6 in renal disease and therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Interleukin-6: from basic biology to selective blockade of pro-inflammatory activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the Lupus Nephritis Assessment with Rituximab study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

23 August 2017

Pharmacokinetic and pharmacodynamic modeling of an anti-interleukin-6 chimeric monoclonal antibody (siltuximab) in patients with metastatic renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

14 September 2017

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

14 September 2017

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

26 June 2018

Properties of a general PK/PD model of antibody-ligand interactions for therapeutic antibodies that bind to soluble endogenous targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

26 June 2018

Interleukin-6 receptor blockage ameliorates murine lupus nephritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

26 June 2018

Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

26 June 2018

Efficacy and safety of abatacept in lupus nephritis: a twelve-month, randomized, double-blind study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

2 September 2018

The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

2 September 2018

Interleukin 6 (IL-6) deficiency delays lupus nephritis in MRL-Faslpr mice: the IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

2 September 2018

American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5129491

2 September 2018

Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FART.39722

21 January 2018

Cytokine IL-6 and IL-10 as Biomarkers in Systemic Lupus Erythematosus

1 reference

https://api.crossref.org/works/10.1002%2FART.39722

21 January 2018

The value of repeat kidney biopsy in quiescent Argentinian lupus nephritis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum and urinary interleukin-6 in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biologic therapy in lupus nephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of renal disease on the standardized mortality ratio and life expectancy of patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic lupus erythematosus disease activity index 2000

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic lupus erythematosus disease activity Index 2000 Responder Index 50: sensitivity to response at 6 and 12 months

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum IL-6, TNFalpha, p55 srTNFalpha, p75srTNFalpha, srIL-2alpha levels and disease activity in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary levels of IL-6 in patients with active lupus nephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27110697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ART.39722

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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