(Q37464076)

English

Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer

scientific article published on December 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

colorectal cancer

1 reference

based on heuristic

inferred from title

0 references

author name string

Sucharita Kundu

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Megan K Brinkmeyer

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Alison L Livingston

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Sheila S David

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

1 December 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1400-1410

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2789978/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population

1 reference

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Cloning, expression, purification and preliminary crystallographic analysis of the RNase HI domain of the Mycobacterium tuberculosis protein Rv2228c as a maltose-binding protein fusion

1 reference

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23 August 2017

Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1

1 reference

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23 August 2017

Characterization of mutant MUTYH proteins associated with familial colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Base-excision repair of oxidative DNA damage

1 reference

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The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair.

1 reference

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23 August 2017

MUTYH-associated polyposis--from defect in base excision repair to clinical genetic testing

1 reference

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23 August 2017

Physical and functional interactions between Escherichia coli MutY glycosylase and mismatch repair protein MutS

1 reference

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23 August 2017

Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis

1 reference

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23 August 2017

Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products

1 reference

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23 August 2017

Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Polymerases leave fingerprints: analysis of the mutational spectrum in Escherichia coli rpoB to assess the role of polymerase IV in spontaneous mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

The role of oxidative stress in carcinogenesis

1 reference

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23 August 2017

Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

DNA-mediated charge transport for DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Endogenous mutagens and the causes of aging and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonucleases of Y150C and G365D murine MYH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Repair of DNA containing Fapy.dG and its beta-C-nucleoside analogue by formamidopyrimidine DNA glycosylase and MutY.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Adenine release is fast in MutY-catalyzed hydrolysis of G:A and 8-Oxo-G:A DNA mismatches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Insight into the functional consequences of inherited variants of the hMYH adenine glycosylase associated with colorectal cancer: complementation assays with hMYH variants and pre-steady-state kinetics of the corresponding mutated E.coli enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

23 August 2017

Evidence that MutY is a monofunctional glycosylase capable of forming a covalent Schiff base intermediate with substrate DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

14 September 2017

A repair system for 8-oxo-7,8-dihydrodeoxyguanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

26 June 2018

Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

Novel findings in Swedish patients with MYH-associated polyposis: mutation detection and clinical characterization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

Insight into the roles of tyrosine 82 and glycine 253 in the Escherichia coli adenine glycosylase MutY.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

DNA damage recognition and repair by the murine MutY homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

Identification of critical residues required for the mutation avoidance function of human MutY (hMYH) and implications in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

Probing the requirements for recognition and catalysis in Fpg and MutY with nonpolar adenine isosteres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

Assistance of maltose binding protein to the in vivo folding of the disulfide-rich C-terminal fragment from Plasmodium falciparum merozoite surface protein 1 expressed in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

Flipping duplex DNA inside out: a double base-flipping reaction mechanism by Escherichia coli MutY adenine glycosylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2789978

2 September 2018

A single engineered point mutation in the adenine glycosylase MutY confers bifunctional glycosylase/AP lyase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutagenesis of the cysteine ligands to the [4Fe-4S] cluster of Escherichia coli MutY

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passing the baton in base excision repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of MUTYH Genotypes and Colorectal Phenotypes in Patients With MUTYH-Associated Polyposis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High frequency of copy-neutral LOH inMUTYH-associated polyposis carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative Nucleobase Modifications Leading to Strand Scission

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemistry of Glycosylases and Endonucleases Involved in Base-Excision Repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity for 8-oxoguanine.adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19836313

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.DNAREP.2009.09.009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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