(Q37470233)

20 August 2017

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title

Cancer's craving for sugar: an opportunity for clinical exploitation (English)

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20 August 2017

4

P Quirke

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author name string

S Yeluri

1

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20 August 2017

B Madhok

2

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20 August 2017

K R Prasad

3

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20 August 2017

D G Jayne

5

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20 August 2017

publication date

5 May 2009

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Journal of Cancer Research and Clinical Oncology

20 August 2017

published in

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20 August 2017

volume

135

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20 August 2017

issue

7

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20 August 2017

page(s)

867-877

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Tumor type M2 pyruvate kinase expression in gastric cancer, colorectal cancer and controls

20 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00432-009-0590-8

Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death

21 January 2018

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Investigating hypoxic tumor physiology through gene expression patterns

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12 December 2020

European Organization for Research and Treatment of Cancer (EORTC) open label phase II study on glufosfamide administered as a 60-minute infusion every 3 weeks in recurrent glioblastoma multiforme.

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12 December 2020

On the Origin of Cancer Cells

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12 December 2020

Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma.

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12 December 2020

Pyruvate kinase M2 (tumor M2-PK) as a screening tool for colorectal cancer (CRC). A review of current published data

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12 December 2020

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

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12 December 2020

Positron emission tomography/magnetic resonance imaging: the next generation of multimodality imaging?

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12 December 2020

ATP citrate lyase inhibition can suppress tumor cell growth

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12 December 2020

Deviant energetic metabolism of glycolytic cancer cells

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12 December 2020

Why do cancers have high aerobic glycolysis?

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12 December 2020

Phase II study of lonidamine and diazepam in the treatment of recurrent glioblastoma multiforme

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12 December 2020

2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer

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12 December 2020

Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays

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12 December 2020

Expression and localization of GLUT1 and GLUT12 in prostate carcinoma

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12 December 2020

Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes

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12 December 2020

GLUT1 glucose transporter expression in colorectal carcinoma: a marker for poor prognosis

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12 December 2020

Glucose catabolism in cancer cells. Isolation, sequence, and activity of the promoter for type II hexokinase

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12 December 2020

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

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12 December 2020

Oxidative metabolism in cancer growth

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12 December 2020

Proteomic analysis of secreted proteins of non-small cell lung cancer

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12 December 2020

An Immunochemical and Immunohistochemical Study of Aldolase Isozymes in Renal Cell Carcinoma

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12 December 2020

Weekly epirubicin plus lonidamine in advanced breast carcinoma

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12 December 2020

Expression of glucose transporter-1 in human gastric carcinoma: association with tumor aggressiveness, metastasis, and patient survival

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12 December 2020

Differential expression of GLUT12 in breast cancer and normal breast tissue

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12 December 2020

Serum phosphohexose isomerase activities in patients with colorectal cancer.

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12 December 2020

Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis?

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12 December 2020

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

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12 December 2020

Glycolytic enzyme activities in breast cancer metastases

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12 December 2020

Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers

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12 December 2020

Serum lactate dehydrogenase levels at presentation predict outcome of patients with limited-stage small-cell lung cancer

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12 December 2020

Expression of type 2 hexokinase and mitochondria-related genes in gastric carcinoma tissues and cell lines.

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12 December 2020

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

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12 December 2020

Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors.

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12 December 2020

Proteomic profiling of proteins dysregulted in Chinese esophageal squamous cell carcinoma

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12 December 2020

Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

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12 December 2020

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

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12 December 2020

Glucose transporter-1 expression in renal cell carcinoma and its correlation with hypoxia inducible factor-1 alpha

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12 December 2020

Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect

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12 December 2020

Tumor 18F-FDG incorporation is enhanced by attenuation of P53 function in breast cancer cells in vitro

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12 December 2020

Tumor autocrine motility factor is an angiogenic factor that stimulates endothelial cell motility

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12 December 2020

Evaluation of long-term treatment of children with congenital lactic acidosis with dichloroacetate

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12 December 2020

An immunohistochemical study on three aldolase isozymes in human lung cancer

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12 December 2020

Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer.

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12 December 2020

Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins.

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12 December 2020

Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited

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12 December 2020

Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

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12 December 2020

Compensatory alterations in energy homeostasis characterized in uterine tumors from hereditary leiomyomatosis and renal cell cancer.

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12 December 2020

Paclitaxel, cisplatin and lonidamine in advanced ovarian cancer. A phase II study

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12 December 2020

Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma.

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12 December 2020

Targeting HIF-1 for cancer therapy

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12 December 2020

Aerobic glycolysis in cancers: implications for the usability of oxygen-responsive genes and fluorodeoxyglucose-PET as markers of tissue hypoxia.

1 reference

12 December 2020

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

1 reference

12 December 2020

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

12 December 2020

Hexokinase-II expression in untreated oral squamous cell carcinoma: comparison with FDG PET imaging

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12 December 2020

Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death

1 reference

12 December 2020

Akt stimulates aerobic glycolysis in cancer cells

1 reference

12 December 2020

Optimizing cancer radiotherapy with 2-deoxy-d-glucose dose escalation studies in patients with glioblastoma multiforme

1 reference

12 December 2020

Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases

1 reference

12 December 2020

Purification and characterization of phosphohexose isomerase from human gastrointestinal carcinoma and its potential relationship to neuroleukin

1 reference

12 December 2020

Protein profiles associated with survival in lung adenocarcinoma

1 reference

12 December 2020

Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL-positive cells

1 reference

12 December 2020

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

1 reference

12 December 2020

Proteome analysis of human lung squamous carcinoma

1 reference

12 December 2020

Prognostic factors in pancreatic carcinoma: serum LDH levels predict survival in metastatic disease

1 reference

12 December 2020

Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide

1 reference

12 December 2020

Oncogenic alterations of metabolism

1 reference

12 December 2020

Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue

1 reference

12 December 2020

Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts

1 reference

12 December 2020

Facilitative glucose transporters

1 reference

12 December 2020

Purification of B16-F1 melanoma autocrine motility factor and its receptor

1 reference

12 December 2020

Tumor autocrine motility factor induces hyperpermeability of endothelial and mesothelial cells leading to accumulation of ascites fluid

1 reference

12 December 2020

Results of high-dose imatinib mesylate in intermediate Sokal risk chronic myeloid leukemia patients in early chronic phase: a phase 2 trial of the GIMEMA CML Working Party

1 reference

12 December 2020

Glufosfamide administered using a 1-hour infusion given as first-line treatment for advanced pancreatic cancer. A phase II trial of the EORTC-new drug development group

1 reference

12 December 2020

Cell metabolism in the regulation of programmed cell death

1 reference

12 December 2020

Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase

1 reference

12 December 2020

Glucose transporters: expression, regulation and cancer.

1 reference

12 December 2020

Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma.

1 reference

12 December 2020

Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer

1 reference

12 December 2020

Fructose-2,6-bisphosphate and control of carbohydrate metabolism in eukaryotes

1 reference

12 December 2020

The diagnostic validity of the serum tumor marker phosphohexose isomerase (PHI) in patients with gastrointestinal, kidney, and breast cancer

1 reference

12 December 2020

Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer

1 reference

12 December 2020

GSK3 promotes arsenite-induced apoptosis via facilitation of mitochondria disruption

1 reference

12 December 2020

Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression.

1 reference

12 December 2020

Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer

1 reference

12 December 2020

Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry

1 reference

12 December 2020

Glycolytic enzymes can modulate cellular life span

1 reference

12 December 2020

Serum lactate dehydrogenase level is a prognostic factor in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy

1 reference

12 December 2020

Positron emission tomography scanning: current and future applications

1 reference

12 December 2020

Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP.

1 reference

12 December 2020

Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma

1 reference

12 December 2020

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

1 reference

12 December 2020

Glufosfamide administered by 1-hour infusion as a second-line treatment for advanced non-small cell lung cancer; a phase II trial of the EORTC-New Drug Development Group

1 reference

12 December 2020

10.1007/S00432-009-0590-8

Identifiers

DOI

1 reference

20 August 2017

1 reference