(Q37477703)

English

Heterologous expression studies of Saccharomyces cerevisiae reveal two distinct trypanosomatid CaaX protease activities and identify their potential targets

scientific article published on 09 October 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Heterologous expression studies of Saccharomyces cerevisiae reveal two distinct trypanosomatid CaaX protease activities and identify their potential targets (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Saccharomyces cerevisiae

1 reference

based on heuristic

inferred from title

author name string

David Z Mokry

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Surya P Manandhar

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Kristen A Chicola

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

George M Santangelo

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Walter K Schmidt

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

9 October 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Eukaryotic Cell

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1891-1900

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Small-molecule inhibitors of the Rce1p CaaX protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Inhibition of the CaaX proteases Rce1p and Ste24p by peptidyl (acyloxy)methyl ketones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Prelamin A farnesylation and progeroid syndromes

1 reference

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23 August 2017

Thematic review series: lipid posttranslational modifications. Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I

1 reference

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23 August 2017

Mutational analysis of the ras converting enzyme reveals a requirement for glutamate and histidine residues

1 reference

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23 August 2017

Thematic review series: lipid posttranslational modifications. Fighting parasitic disease by blocking protein farnesylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Signalling the genome: the Ras-like small GTPase family of trypanosomatids

1 reference

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23 August 2017

The isoprenoid substrate specificity of isoprenylcysteine carboxylmethyltransferase: development of novel inhibitors

1 reference

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23 August 2017

Yeast as a tractable genetic system for functional studies of the insulin-degrading enzyme

1 reference

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23 August 2017

A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.

1 reference

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23 August 2017

Farnesyltransferase inhibitors as anticancer agents: current status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Functional profiling of the Saccharomyces cerevisiae genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Farnesyltransferase inhibitors: promises and realities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Human ras-converting enzyme (hRCE1) endoproteolytic activity on K-ras-derived peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Solid-phase synthesis of a farnesylated CaaX peptide library: inhibitors of the Ras CaaX endoprotease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Studies with recombinant Saccharomyces cerevisiae CaaX prenyl protease Rce1p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

A biochemical genomics approach for identifying genes by the activity of their products.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Cloning and characterization of a mammalian prenyl protein-specific protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Modulation of Ras and a-factor function by carboxyl-terminal proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Recombination-mediated PCR-directed plasmid construction in vivo in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

The a-factor pheromone of Saccharomyces cerevisiae is essential for mating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Sequence dependence of protein isoprenylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Endoproteolytic processing of a farnesylated peptide in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

A simple and efficient procedure for transformation of yeasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

23 August 2017

Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

6 September 2017

C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

26 June 2018

Transcription and regulatory signals at the mating type locus in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

26 June 2018

Maturation of isoprenylated proteins in Saccharomyces cerevisiae. Multiple activities catalyze the cleavage of the three carboxyl-terminal amino acids from farnesylated substrates in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

26 June 2018

Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

2 September 2018

Benzophenone-based farnesyltransferase inhibitors with high activity against Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

2 September 2018

AtFACE-2, a functional prenylated protein protease from Arabidopsis thaliana related to mammalian Ras-converting enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

2 September 2018

Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

2 September 2018

The Arabidopsis AtSTE24 is a CAAX protease with broad substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794219

2 September 2018

Reconstitution of the Ste24p-dependent N-terminal proteolytic step in yeast a-factor biogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-peptidic, non-prenylic inhibitors of the prenyl protein-specific protease Rce1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prenylated protein-specific endoprotease in rat liver microsomes that produces a carboxyl-terminal tripeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate characterization of the Saccharomyces cerevisiae protein farnesyltransferase and type-I protein geranylgeranyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-prenylation-processing enzymes as new targets in oncogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19820121

12 December 2020

based on heuristic

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Identifiers

10.1128/EC.00169-09

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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