(Q37478284)

20 August 2017

New metabolites of fenofibrate in Sprague-Dawley rats by UPLC-ESI-QTOF-MS-based metabolomics coupled with LC-MS/MS (English)

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20 August 2017

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A Liu

1

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20 August 2017

Y Chen

2

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20 August 2017

Z Yang

3

1 reference

20 August 2017

Y Feng

4

1 reference

20 August 2017

W Rui

5

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20 August 2017

W Luo

6

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20 August 2017

Y Liu

7

1 reference

20 August 2017

F J Gonzalez

8

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20 August 2017

R Dai

9

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20 August 2017

language of work or name

English

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publication date

1 April 2009

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20 August 2017

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20 August 2017

39

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20 August 2017

4

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20 August 2017

345-354

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describes a project that uses

20 August 2017

liquid chromatography–mass spectrometry

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liquid chromatography-tandem mass spectrometry

inferred from title

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PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

LC-MS-based metabolomics in drug metabolism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Metabolomic and genetic analysis of biomarkers for peroxisome proliferator-activated receptor alpha expression and activation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Hepatocyte-restricted constitutive activation of PPAR alpha induces hepatoproliferation but not hepatocarcinogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

PPAR{alpha} mediates the hypolipidemic action of fibrates by antagonizing FoxO1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Metabolomics: from pattern recognition to biological interpretation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Metabonomics: systems biology in pharmaceutical research and development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

PPARalpha agonist-induced rodent tumors: modes of action and human relevance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Comparative toxicity and safety profile of fenofibrate and other fibric acid derivatives

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Peroxisome proliferation and hepatocarcinogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Fenofibrate: metabolism and species differences for peroxisome proliferation in cultured hepatocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Relative safety of gemfibrozil and fenofibrate in the absence of concomitant cerivastatin use.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

The application of microbore UPLC/oa-TOF-MS and 1H NMR spectroscopy to the metabonomic analysis of rat urine following the intravenous administration of pravastatin.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Statins and PPARalpha agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Fenofibrate-induced myopathy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Fenofibrate impairs rat mitochondrial function by inhibition of respiratory complex I.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Role of the peroxisome proliferator-activated receptors (PPARS) in the regulation of lipids and inflammation control

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Fenofibrate-Induced elevation in serum creatinine

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

The metabolism and disposition of 14C-fenofibrate in human volunteers

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2794380

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F00498250802680827

Clofibrate and clofibric acid: comparison of the metabolic disposition in rats and dogs

21 January 2018

1 reference

12 December 2020

Species differences in the metabolic conjugation of clofibric acid and clofibrate in laboratory animals and man

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12 December 2020

The metabolism and disposition of fenofibrate in rat, guinea pig, and dog

1 reference

12 December 2020

Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice

1 reference

12 December 2020

10.1080/00498250802680827

Identifiers

DOI

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release_f3ahriibqbgwhicnutziemgpau

20 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/f3ahriibqbgwhicnutziemgpau

24 November 2022

mapped directly with Wikidata item

1 reference

20 August 2017

PubMed publication ID

19350456

1 reference