(Q37483492)

20 August 2017

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title

From genes to function: the next challenge to understanding multiple sclerosis (English)

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20 August 2017

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2

Manuel A Friese

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20 August 2017

1

Lars Fugger

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20 August 2017

John I Bell

3

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20 August 2017

publication date

1 June 2009

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Nature Reviews Immunology

20 August 2017

published in

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20 August 2017

volume

9

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20 August 2017

issue

6

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20 August 2017

page(s)

408-417

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CD226 Gly307Ser association with multiple autoimmune diseases

20 August 2017

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Genetics of multiple sclerosis

31 March 2020

2 references

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31 March 2020

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease

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Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis.

31 March 2020

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HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis

31 March 2020

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Risk alleles for multiple sclerosis identified by a genomewide study

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Variation in interleukin 7 receptor α chain (IL7R) influences risk of multiple sclerosis

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Decoding the epigenetic language of neuronal plasticity

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Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex

31 March 2020

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Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis

31 March 2020

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Applications of DNA tiling arrays for whole-genome analysis

31 March 2020

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Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

31 March 2020

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The value of animal models for drug development in multiple sclerosis.

31 March 2020

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Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab

31 March 2020

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Functional epistasis on a common MHC haplotype associated with multiple sclerosis

31 March 2020

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A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

31 March 2020

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Alemtuzumab vs. interferon beta-1a in early multiple sclerosis

31 March 2020

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Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

31 March 2020

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A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

31 March 2020

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31 March 2020

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The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

31 March 2020

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Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes

31 March 2020

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EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-gamma and IL-2

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis

31 March 2020

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Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.

31 March 2020

1 reference

Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system

31 March 2020

1 reference

Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.

31 March 2020

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31 March 2020

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31 March 2020

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Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

31 March 2020

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Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis

31 March 2020

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Multiple sclerosis: a complicated picture of autoimmunity.

31 March 2020

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The relation between inflammation and neurodegeneration in multiple sclerosis brains.

31 March 2020

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Multiple sclerosis--the plaque and its pathogenesis

31 March 2020

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Multistep pathogenesis of autoimmune disease.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI2554

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20 August 2017

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