(Q37484223)

20 August 2017

Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG (English)

1 reference

20 August 2017

1 reference

Aran F Labrijn

4

0 references

author name string

Rebecca J Rose

1

1 reference

20 August 2017

Patrick H C van Berkel

2

1 reference

20 August 2017

Ewald T J van den Bremer

3

1 reference

20 August 2017

Tom Vink

5

1 reference

20 August 2017

Janine Schuurman

6

1 reference

20 August 2017

Albert J R Heck

7

1 reference

20 August 2017

Paul W H I Parren

8

1 reference

20 August 2017

13 February 2013

1 reference

20 August 2017

Monoclonal Antibodies

1 reference

20 August 2017

5

1 reference

20 August 2017

2

1 reference

20 August 2017

219-228

1 reference

A novel role for the IgG Fc glycan: the anti-inflammatory activity of sialylated IgG Fcs.

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Post-translational modifications differentially affect IgG1 conformation and receptor binding.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

A close look at human IgG sialylation and subclass distribution after lectin fractionation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Identification of a receptor required for the anti-inflammatory activity of IVIG.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Terminal sugars of Fc glycans influence antibody effector functions of IgGs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

The impact of glycosylation on the biological function and structure of human immunoglobulins.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Control of recombinant monoclonal antibody effector functions by Fc N-glycan remodeling in vitro

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Glycosylation of recombinant antibody therapeutics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Sialylation of human IgG-Fc carbohydrate by transfected rat alpha2,6-sialyltransferase.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Bispecific human IgG by design

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

The role of N-linked oligosaccharides in glycoprotein function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Effect of C2-associated carbohydrate structure on Ig effector function: studies with chimeric mouse-human IgG1 antibodies in glycosylation mutants of Chinese hamster ovary cells.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fc gamma receptor I and influence the synthesis of its oligosaccharide chains.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Effects of galactose depletion from oligosaccharide chains on immunological activities of human IgG.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Conformational changes in oxidatively stressed monoclonal antibodies studied by hydrogen exchange mass spectrometry

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Rapid production of recombinant human IgG With improved ADCC effector function in a transient expression system

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

N-linked glycosylation is an important parameter for optimal selection of cell lines producing biopharmaceutical human IgG.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Glycosylation: heterogeneity and the 3D structure of proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Marketed therapeutic antibodies compendium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893232

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FMABS.23532

Quantitative Analysis of the Interaction Strength and Dynamics of Human IgG4 Half Molecules by Native Mass Spectrometry

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FMABS.23532

Characterization of IgG1 Conformation and Conformational Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FMABS.23532

'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23406897

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression and characterization of truncated forms of humanized L243 IgG1. Architectural features can influence synthesis of its oligosaccharide chains and affect superoxide production triggered through human Fcgamma receptor I

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23406897

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intramolecular Glycan–Protein Interactions in Glycoproteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23406897

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/MABS.23532

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

23406897

1 reference