(Q30384877)

14 October 2017

Post-translational modifications differentially affect IgG1 conformation and receptor binding. (English)

1 reference

14 October 2017

John R Engen

4

0 references

author name string

Damian Houde

series ordinal

1

1 reference

PMCID

2938052

14 October 2017

Yucai Peng

series ordinal

2

1 reference

PMCID

2938052

14 October 2017

Steven A Berkowitz

series ordinal

3

1 reference

14 October 2017

26 January 2010

1 reference

Molecular & Cellular Proteomics

14 October 2017

1 reference

14 October 2017

9

1 reference

14 October 2017

8

1 reference

14 October 2017

1716-1728

1 reference

Analysis of protein conformation and dynamics by hydrogen/deuterium exchange MS.

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Glycosylation as a strategy to improve antibody-based therapeutics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

High-speed and high-resolution UPLC separation at zero degrees Celsius

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Determination of protein structures--a series of fortunate events

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Oxidation of calmodulin alters activation and regulation of CaMKII.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Solution NMR of large molecules and assemblies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Non-fucosylated therapeutic antibodies as next-generation therapeutic antibodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Post-translational modifications in the context of therapeutic proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

The impact of glycosylation on the biological function and structure of human immunoglobulins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Semi-automated data processing of hydrogen exchange mass spectra using HX-Express

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Potent antibody therapeutics by design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Glycoform-dependent conformational alteration of the Fc region of human immunoglobulin G1 as revealed by NMR spectroscopy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Protein posttranslational modifications: the chemistry of proteome diversifications

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Hydrogen exchange mass spectrometry for the analysis of protein dynamics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Fucose depletion from human IgG1 oligosaccharide enhances binding enthalpy and association rate between IgG1 and FcgammaRIIIa

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Mass spectrometry-based proteomics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Recognition of immunoglobulins by Fcgamma receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Role of oligosaccharide residues of IgG1-Fc in Fc gamma RIIb binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

The structure of a human type III Fcgamma receptor in complex with Fc

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Speeding molecular recognition by using the folding funnel: the fly-casting mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Identification of protein-protein interfaces by decreased amide proton solvent accessibility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

IgG-Fc-mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Probing the non-covalent structure of proteins by amide hydrogen exchange and mass spectrometry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

How to measure and predict the molar absorption coefficient of a protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

The effects of phosphorylation on the structure and function of proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

A broad range of Fab stabilities within a host of therapeutic IgGs.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

Impact of methionine oxidation on the binding of human IgG1 to Fc Rn and Fc gamma receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

Physicochemical and biological assays for quality control of biopharmaceuticals: interferon alpha-2 case study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

In vitro galactosylation of human IgG at 1 kg scale using recombinant galactosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

Assessment of the repeatability and reproducibility of hydrogen/deuterium exchange mass spectrometry measurements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

Structure and stability changes of human IgG1 Fc as a consequence of methionine oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

Analysis of protein complexes with hydrogen exchange and mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900540-MCP200

A comparison of ALPHAScreen, TR-FRET, and TRF as assay methods for FXR nuclear receptors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938052

The effect of the removal of sialic acid, galactose and total carbohydrate on the functional activity of Campath-1H

26 November 2018

1 reference

12 December 2020

Mass spectrometric determination of isotopic exchange rates of amide hydrogens located on the surfaces of proteins

1 reference

12 December 2020

Determination of protein oxidation by mass spectrometry and method transfer to quality control

1 reference

12 December 2020

Solution NMR of supramolecular complexes: providing new insights into function

1 reference

12 December 2020

10.1074/MCP.M900540-MCP200

Identifiers

DOI

1 reference

14 October 2017

1 reference

14 October 2017

1 reference

PMCID

2938052