(Q37488431)

English

Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice

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1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Niels Christian Danbolt

9

1 reference

Europe PubMed Central

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20 August 2017

1

object named as

Yun Zhou

1 reference

Europe PubMed Central

20 August 2017

PMC publication ID

Leonie F Waanders

2

object named as

Leonie F Waanders

1 reference

Europe PubMed Central

20 August 2017

PMC publication ID

Silvia Holmseth

3

object named as

Silvia Holmseth

1 reference

Europe PubMed Central

20 August 2017

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4

object named as

Caiying Guo

1 reference

Europe PubMed Central

20 August 2017

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5

object named as

Urs V Berger

1 reference

Europe PubMed Central

20 August 2017

PMC publication ID

6

object named as

Yuchuan Li

1 reference

Europe PubMed Central

20 August 2017

PMC publication ID

Anne-Catherine Lehre

7

object named as

Anne-Catherine Lehre

1 reference

Europe PubMed Central

20 August 2017

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8

object named as

Knut P Lehre

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Europe PubMed Central

20 August 2017

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language of work or name

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publication date

26 November 2013

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Europe PubMed Central

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20 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

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20 August 2017

289

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

1329-1344

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

The rates of postmortem proteolysis of glutamate transporters differ dramatically between cells and between transporter subtypes

1 reference

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Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.

1 reference

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Specificity controls for immunocytochemistry: the antigen preadsorption test can lead to inaccurate assessment of antibody specificity.

1 reference

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Differential expression of the glutamate transporter GLT-1 in pancreas

1 reference

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1 reference

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The complex mechanism of glutamate dehydrogenase in insulin secretion

1 reference

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A role for glutamate transporters in the regulation of insulin secretion

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1 reference

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1 reference

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1 reference

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Regulation of insulin secretion: role of mitochondrial signalling

1 reference

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Microscopic anatomy of the human islet of Langerhans

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Quantitative proteomic analysis of single pancreatic islets

1 reference

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The concentrations and distributions of three C-terminal variants of the GLT1 (EAAT2; slc1a2) glutamate transporter protein in rat brain tissue suggest differential regulation

1 reference

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MFng is dispensable for mouse pancreas development and function

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Detailed transcriptome atlas of the pancreatic beta cell

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Genome-wide analysis of pancreatic cancer using microarray-based techniques

1 reference

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MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

1 reference

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A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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The orphan transporter Rxt1/NTT4 (SLC6A17) functions as a synaptic vesicle amino acid transporter selective for proline, glycine, leucine, and alanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Characterization of the mouse pancreatic islet proteome and comparative analysis with other mouse tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis

1 reference

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Glutamate transporters: confining runaway excitation by shaping synaptic transmission

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Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement

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In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

1 reference

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The genetics of heteromeric amino acid transporters

1 reference

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CATs and HATs: the SLC7 family of amino acid transporters

1 reference

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Glutamate-mediated signaling in the islets of Langerhans: a thread entangled

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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Of mice and MEN1: Insulinomas in a conditional mouse knockout

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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A highly efficient recombineering-based method for generating conditional knockout mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Glutamate uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Glutamate, at the interface between amino acid and carbohydrate metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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Newer aspects of glutamine/glutamate metabolism: the role of acute pH changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Molecular and functional analysis of SDCT2, a novel rat sodium-dependent dicarboxylate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Expression of the glial glutamate transporter EAAT2 in the human CNS: an immunohistochemical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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Cloning and expression of a cDNA encoding the transporter of taurine and beta-alanine in mouse brain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Cloning and expression of a rat brain L-glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

23 August 2017

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

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An overview of a wide range of functions of ZnT and Zip zinc transporters in the secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

6 September 2017

The role of amino acid transporters in inherited and acquired diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

6 September 2017

Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

6 September 2017

Amino acids and diabetes: implications for endocrine, metabolic and immune function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

6 September 2017

Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

6 September 2017

Cloning and functional characterization of a system ASC-like Na+-dependent neutral amino acid transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

6 September 2017

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1 reference

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14 September 2017

Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

14 September 2017

Characterization of vesicular glutamate transporter in pancreatic alpha - and beta -cells and its regulation by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

14 September 2017

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

1 reference

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14 September 2017

A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

28 September 2017

The rat hepatoma cell line H4-II-E-C3 expresses high activities of the high-affinity glutamate transporter GLT-1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

28 September 2017

A novel chromatographic method allows on-line reanalysis of the proteome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

28 September 2017

Glutamate exocrine dynamics augmented by plasma glutamine and the distribution of amino acid transporters of the rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

Specificity of immunoreactions: the importance of testing specificity in each method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

Segregation of two glutaminase isoforms in islets of Langerhans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

A signaling role of glutamine in insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

Interindividual differences in the levels of the glutamate transporters GLAST and GLT, but no clear correlation with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

Glutamate stimulates insulin secretion and improves glucose tolerance in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

Purification and reconstitution of the sodium- and potassium-coupled glutamate transport glycoprotein from rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

An [Na+ + K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

26 June 2018

Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Comprehensive description of the N-glycoproteome of mouse pancreatic β-cells and human islets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Behavioral characterization of GLT1 (+/-) mice as a model of mild glutamatergic hyperfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Improvement of pancreatic islet isolation outcomes using glutamine perfusion during isolation procedure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Nestin expression in pancreatic exocrine cell lineages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Cloning and characterization of the 3'-untranslated region of the human excitatory amino acid transporter 2 transcript

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Localization and function of group III metabotropic glutamate receptors in rat pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Glutamate is not a major conveyer of ATP-sensitive K+ channel-independent glucose action in pancreatic islet beta cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Comparative analysis of glutamate transporter expression in rat brain using differential double in situ hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

A monoclonal antibody raised against an [Na(+)+K+]coupled L-glutamate transporter purified from rat brain confirms glial cell localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894318

2 September 2018

Acridine orange induces translocation of phosphatidylserine to red blood cell surface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.529065

21 January 2018

Improvement of Pancreatic Islet Isolation Outcomes Using Glutamine Perfusion during Isolation Procedure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.529065

21 January 2018

Localization of transporters using transporter-specific antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a glutamate transporter cDNA in human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies as valuable neuroscience research tools versus reagents of mass distraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of antibodies: unexpected cross-reactivity of antibodies directed against the excitatory amino acid transporter 3 (EAAT3)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutaminase activity is confined to the mantle of the islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of factors affecting glutamate concentrations in the whole blood of healthy human volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural morphometry of the pancreatic ?-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate ingestion: the plasma and muscle free amino acid pools of resting humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-induced insulin release in islets of young rats: time-dependent potentiation and effects of 2-bromostearate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity controls for immunocytochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate is not a messenger in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/24280215

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.529065

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Semantic Scholar paper ID

c67e13345dbb908edcd54ad420c7a80098e708fc

0 references

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