(Q34997990)

English

Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets (English)

1 reference

Europe PubMed Central

5 August 2017

12

object named as

Jon Odorico

1 reference

Europe PubMed Central

5 August 2017

author name string

Michael J MacDonald

1

1 reference

Europe PubMed Central

5 August 2017

Melissa J Longacre

2

1 reference

Europe PubMed Central

5 August 2017

Scott W Stoker

3

1 reference

Europe PubMed Central

5 August 2017

Mindy Kendrick

4

1 reference

Europe PubMed Central

5 August 2017

Ansaya Thonpho

5

1 reference

Europe PubMed Central

5 August 2017

Laura J Brown

6

1 reference

Europe PubMed Central

5 August 2017

Noaman M Hasan

7

1 reference

Europe PubMed Central

5 August 2017

Sarawut Jitrapakdee

8

1 reference

Europe PubMed Central

5 August 2017

Toshiyuki Fukao

9

1 reference

Europe PubMed Central

5 August 2017

Matthew S Hanson

10

1 reference

Europe PubMed Central

5 August 2017

Luis A Fernandez

11

1 reference

Europe PubMed Central

5 August 2017

language of work or name

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publication date

22 March 2011

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Europe PubMed Central

5 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

5 August 2017

286

1 reference

Europe PubMed Central

5 August 2017

21

1 reference

Europe PubMed Central

5 August 2017

18383-18396

1 reference

Europe PubMed Central

5 August 2017

Quantitative analysis of cell composition and purity of human pancreatic islet preparations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Islet architecture: A comparative study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Lower succinyl-CoA:3-ketoacid-CoA transferase (SCOT) and ATP citrate lyase in pancreatic islets of a rat model of type 2 diabetes: knockdown of SCOT inhibits insulin release in rat insulinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Regulation of insulin secretion: role of mitochondrial signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Meta-analysis of gene expression in human pancreatic islets after in vitro expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Elimination of KATP channels in mouse islets results in elevated [U-13C]glucose metabolism, glutaminolysis, and pyruvate cycling but a decreased gamma-aminobutyric acid shunt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Capillary LC-MS for high sensitivity metabolomic analysis of single islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Acetoacetate and beta-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

The role of rapid lipogenesis in insulin secretion: Insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Synergistic potent insulin release by combinations of weak secretagogues in pancreatic islets and INS-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Anaplerotic molecules: current and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Insights into the role of anaplerosis in insulin secretion: A 13C NMR study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

The RIN: an RNA integrity number for assigning integrity values to RNA measurements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Involvement of specific proteins (Sp1/Sp3) and nuclear factor Y in basal transcription of the distal promoter of the rat pyruvate carboxylase gene in beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

The export of metabolites from mitochondria and anaplerosis in insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Sp/Krüppel-like transcription factors are essential for the expression of mitochondrial glycerol phosphate dehydrogenase promoter B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

The key role of anaplerosis and cataplerosis for citric acid cycle function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Functional analysis of two promoters for the human mitochondrial glycerol phosphate dehydrogenase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Sequence and tissue-dependent RNA expression of mouse FAD-linked glycerol-3-phosphate dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

High content of mitochondrial glycerol-3-phosphate dehydrogenase in pancreatic islets and its inhibition by diazoxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Controls of citrate synthase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

A 14CO2 ratios method for detecting pyruvate carboxylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

High activity of mitochondrial glycerol phosphate dehydrogenase in insulinomas and carcinoid and other tumors of the amine precursor uptake decarboxylation system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Impairment of Glycerol Phosphate Shuttle in Islets From Rats With Diabetes Induced by Neonatal Streptozocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Glucose regulation of acetyl-CoA carboxylase in hepatoma and islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Nicotinamide adenine dinucleotide phosphate-converting enzymes and adenosine triphosphate citrate lyase in some tissues and organs of New Zealand obese mice with special reference to the enzyme pattern of the pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099655

8 July 2018

Critical role for cataplerosis via citrate in glucose-regulated insulin release

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.241182

21 January 2018

Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.241182

21 January 2018

Survey of normal appearing mouse strain which lacks malic enzyme and Nad+-linked glycerol phosphate dehydrogenase: normal pancreatic beta cell function, but abnormal metabolite pattern in skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.241182

21 January 2018

Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.241182

21 January 2018

Estimates of glycolysis, pyruvate (de)carboxylation, pentose phosphate pathway, and methyl succinate metabolism in incapacitated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose enters mitochondrial metabolism via both carboxylation and decarboxylation of pyruvate in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying the carboxylation of pyruvate in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paths of carbon in gluconeogenesis and lipogenesis. 3. The role and regulation of mitochondrial processes involved in supplying precursors of phosphoenolpyruvate

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of citric acid cycle activity in rat heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavin content of intracellular compartments of pancreatic islets compared with acinar tissue and liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the malate aspartate shuttle in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased Mitochondrial Glycerol Phosphate Dehydrogenase Activity in Insulinomas of Two Hypoglycemic Infants*

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of beta-hydroxybutyrate and acetoacetate on insulin and glucagon secretion from perfused rat pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketone bodies and islet function: 45Ca handling, insulin synthesis, and release

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate dehydrogenase and pyruvate carboxylase. Sites of pretranslational regulation by glucose of glucose-induced insulin release in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of Glyconeogenesis in Pancreatic Islets: Expression of Gluconeogenic Enzyme Genes in Islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutrient control of insulin secretion in isolated normal human islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superiority of small islets in human islet transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the insulin secretagogue methyl succinate by pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/21454710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.241182

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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