(Q37496563)

English

Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity

scientific article published on 29 August 2013

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity (English)

1 reference

Europe PubMed Central

20 August 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

Whitney Shatz

1

1 reference

Europe PubMed Central

20 August 2017

Shan Chung

2

1 reference

Europe PubMed Central

20 August 2017

Bing Li

3

1 reference

Europe PubMed Central

20 August 2017

Brett Marshall

4

1 reference

Europe PubMed Central

20 August 2017

Max Tejada

5

1 reference

Europe PubMed Central

20 August 2017

Wilson Phung

6

1 reference

Europe PubMed Central

20 August 2017

Wendy Sandoval

7

1 reference

Europe PubMed Central

20 August 2017

Robert F Kelley

8

1 reference

Europe PubMed Central

20 August 2017

Justin M Scheer

9

1 reference

Europe PubMed Central

20 August 2017

publication date

29 August 2013

1 reference

Europe PubMed Central

20 August 2017

Monoclonal Antibodies

1 reference

Europe PubMed Central

20 August 2017

5

1 reference

Europe PubMed Central

20 August 2017

6

1 reference

Europe PubMed Central

20 August 2017

872-881

1 reference

Europe PubMed Central

20 August 2017

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Revisiting the role of glycosylation in the structure of human IgG Fc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Characterization of IgG N-glycans employing a microfluidic chip that integrates glycan cleavage, sample purification, LC separation, and MS detection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Glycosylation as a strategy to improve antibody-based therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Rituximab: ongoing and future clinical development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

The structure of a human type III Fcgamma receptor in complex with Fc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Glycosylation and the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

IgG-Fc-mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

An efficient route to human bispecific IgG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

23 August 2017

Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

6 September 2017

The carbohydrate at FcgammaRIIIa Asn-162. An element required for high affinity binding to non-fucosylated IgG glycoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

6 September 2017

Fucose depletion from human IgG1 oligosaccharide enhances binding enthalpy and association rate between IgG1 and FcgammaRIIIa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

6 September 2017

Development of a quantitative, cell-line based assay to measure ADCC activity mediated by therapeutic antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

6 September 2017

The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

14 September 2017

Development of a serum-free culture medium for the large scale production of recombinant protein from a Chinese hamster ovary cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

28 September 2017

Clinical significance of IgG Fc receptors and Fc gamma R-directed immunotherapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

28 September 2017

Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

26 June 2018

Effect of glycosylation on antibody function: implications for genetic engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

26 June 2018

A high throughput electrochemiluminescent cell-binding assay for therapeutic anti-CD20 antibody selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

2 September 2018

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3896601

2 September 2018

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/23995614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of IgG1 with asymmetrical Fc glycosylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23995614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced antitumor effects of CD20 over CD19 monoclonal antibodies in a nude mouse xenograft model

1 reference

https://pubmed.ncbi.nlm.nih.gov/23995614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/MABS.26307

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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