(Q37498285)

20 August 2017

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title

Fibroblast activation and myofibroblast generation in obstructive nephropathy (English)

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20 August 2017

María T Grande

1

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20 August 2017

José M López-Novoa

series ordinal

2

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20 August 2017

language of work or name

English

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publication date

1 June 2009

1 reference

Nature Reviews Nephrology

20 August 2017

published in

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20 August 2017

volume

5

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20 August 2017

issue

6

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20 August 2017

page(s)

319-328

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https://scigraph.springernature.com/pub.10.1038/nrneph.2009.74

20 August 2017

exact match

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cites work

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Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat.

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Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

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Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition

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Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis

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Involvement of renal progenitor tubular cells in epithelial-to-mesenchymal transition in fibrotic rat kidneys

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Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys

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The renal cortical interstitium: morphological and functional aspects

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Antibodies against macrophages that overlap in specificity with fibroblasts.

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Tissue repair, contraction, and the myofibroblast

31 March 2020

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Cyclooxygenase-2 inhibitor decreases extracellular matrix synthesis in stretched renal fibroblasts

31 March 2020

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Transforming growth factor-beta and Smad signalling in kidney diseases.

31 March 2020

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PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation

31 March 2020

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Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission

31 March 2020

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Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice

31 March 2020

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Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease

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Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

31 March 2020

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Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation.

31 March 2020

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Ubiquitin-dependent degradation of SnoN and Ski is increased in renal fibrosis induced by obstructive injury

31 March 2020

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Activin A is a potent activator of renal interstitial fibroblasts

31 March 2020

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Tight junction biology and kidney dysfunction

31 March 2020

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

31 March 2020

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Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis

31 March 2020

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Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies

31 March 2020

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Fibroblast-specific protein 1 is a specific prognostic marker for renal survival in patients with IgAN.

31 March 2020

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Immunolocalization of fibroblast growth factor-1 (FGF-1), its receptor (FGFR-1), and fibroblast-specific protein-1 (FSP-1) in inflammatory renal disease

31 March 2020

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Risk Factors for Early Epithelial to Mesenchymal Transition in Renal Grafts

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Epithelial to mesenchymal transition during late deterioration of human kidney transplants: the role of tubular cells in fibrogenesis

31 March 2020

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Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

PINCH-1 promotes tubular epithelial-to-mesenchymal transition by interacting with integrin-linked kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Increased E-cadherin expression in the ligated kidney following unilateral ureteric obstruction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Collecting duct epithelial-mesenchymal transition in fetal urinary tract obstruction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Snail1 is involved in the renal epithelial-mesenchymal transition.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Twist relates to tubular epithelial-mesenchymal transition and interstitial fibrogenesis in the obstructed kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Role of Ras signaling in the induction of snail by transforming growth factor-beta.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Transforming growth factor-beta1 represses E-cadherin production via slug expression in lens epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Complex networks orchestrate epithelial-mesenchymal transitions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Metastasis and AKT activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Activation of Erk1/2 and Akt following unilateral ureteral obstruction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Role of Wnt/beta-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

A hypoxic twist in metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Integrin-linked kinase--essential roles in physiology and cancer biology.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

ILK, PINCH and parvin: the tIPP of integrin signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Smad3 deficiency attenuates renal fibrosis, inflammation,and apoptosis after unilateral ureteral obstruction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Transforming growth factor-beta signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

TGF-beta and epithelial-to-mesenchymal transitions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

A proximal activator of transcription in epithelial-mesenchymal transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

HSP27 is involved in the pathogenesis of kidney tubulointerstitial fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Tissue inhibitor of metalloproteinase-1 exacerbated renal interstitial fibrosis through enhancing inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

MMP-2 inhibition reduces renal macrophage infiltration with increased fibrosis in UUO

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Matrilysin (MMP-7) expression in renal tubular damage: association with Wnt4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

RhoGTPase activation is a key step in renal epithelial mesenchymal transdifferentiation

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

The role of epithelial-mesenchymal transition in cancer pathology

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Therapeutical relevance of MAP-kinase inhibitors in renal diseases: current knowledge and future clinical perspectives.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2009.74

The Rho-ROCK system as a new therapeutic target for preventing interstitial fibrosis

31 March 2020

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12 December 2020

Biochemical-molecular markers in unilateral ureteral obstruction.

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12 December 2020

TGFbeta3-induced activation of RhoA/Rho-kinase pathway is necessary but not sufficient for epithelio-mesenchymal transdifferentiation: implications for palatogenesis

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12 December 2020

On the pathogenesis of chronic renal failure in primary glomerulopathies: a view from the interstitium

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12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2009.74

1 reference

Dimensions Publication ID

20 August 2017

1047113108

0 references

1 reference