(Q37511619)

English

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial.

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863809%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863809%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

phase III clinical trial

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Alzheimer's disease

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0 references

2

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27 March 2020

Charles Harrington

17

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27 March 2020

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Peter Bentham

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27 March 2020

author name string

Serge Gauthier

1

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27 March 2020

Lon S Schneider

3

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27 March 2020

Gordon K Wilcock

4

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27 March 2020

Giovanni B Frisoni

5

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27 March 2020

Jiri H Hardlund

6

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27 March 2020

Hans J Moebius

7

1 reference

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27 March 2020

Karin A Kook

9

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27 March 2020

Damon J Wischik

10

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27 March 2020

Bjoern O Schelter

11

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27 March 2020

Charles S Davis

12

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27 March 2020

Roger T Staff

13

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27 March 2020

Luc Bracoud

14

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27 March 2020

Kohkan Shamsi

15

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27 March 2020

John M D Storey

16

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27 March 2020

Claude M Wischik

18

1 reference

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27 March 2020

language of work or name

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publication date

16 November 2016

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27 March 2020

1 reference

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27 March 2020

388

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27 March 2020

2873-2884

1 reference

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27 March 2020

10062

1 reference

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27 March 2020

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

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Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults

1 reference

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23 August 2017

Role of P-glycoprotein in mediating rivastigmine effect on amyloid-β brain load and related pathology in Alzheimer's disease mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Complex Disposition of Methylthioninium Redox Forms Determines Efficacy in Tau Aggregation Inhibitor Therapy for Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Tau-aggregation inhibitor therapy for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults

1 reference

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23 August 2017

The clinical use of structural MRI in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Structural characterization of the core of the paired helical filament of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

23 August 2017

Defeating Alzheimer's disease and other dementias: a priority for European science and society

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

6 September 2017

Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

6 September 2017

Alzheimer's therapeutics: continued clinical failures question the validity of the amyloid hypothesis-but what lies beyond?

1 reference

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6 September 2017

Erratum: Lai, R.Y.K.; Harrington, C.R.; Wischik, C.M. Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease. Biomolecules 2016, 6, 19

1 reference

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26 June 2018

Pharmacokinetics of Highly Ionized Drugs II: Methylene Blue—Absorption, Metabolism, and Excretion in Man and Dog after Oral Administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

26 June 2018

Subunit structure of paired helical filaments in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

26 June 2018

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5164296

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Brain white matter hyperintensities: relative importance of vascular risk factors in nondemented elderly people

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2 September 2018

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

1 reference

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2 September 2018

The pathological process underlying Alzheimer's disease in individuals under thirty

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple Testing of General Contrasts Using Logical Constraints and Correlations

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2931275-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2931275-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Serotonin syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/27863809

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0140-6736(16)31275-2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863809%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863809%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27863809%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

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