(Q37520006)

20 August 2017

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title

Cells and prions: a license to replicate (English)

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20 August 2017

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2

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20 August 2017

3

Mathias Heikenwalder

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Mario Nuvolone

object named as

Mario Nuvolone

series ordinal

1

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language of work or name

English

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publication date

13 June 2009

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20 August 2017

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20 August 2017

volume

583

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20 August 2017

issue

16

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20 August 2017

page(s)

2674-2684

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Molecular neurology of prion disease

20 August 2017

cites work

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Prions and their lethal journey to the brain

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Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native population

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A new variant of Creutzfeldt-Jakob disease in the UK.

21 January 2018

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Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion.

21 January 2018

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Prion infections, blood and transfusions

21 January 2018

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Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication

21 January 2018

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PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice

21 January 2018

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Prion biology: the quest for the test.

21 January 2018

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Kuru in the 21st century--an acquired human prion disease with very long incubation periods

21 January 2018

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Identification and characterization of two bovine spongiform encephalopathy cases diagnosed in the United States

21 January 2018

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Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease

21 January 2018

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A prion disease of cervids: chronic wasting disease

21 January 2018

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Prions, cytokines, and chemokines: a meeting in lymphoid organs

21 January 2018

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Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease

21 January 2018

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Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease

21 January 2018

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Infectious prions in the saliva and blood of deer with chronic wasting disease

21 January 2018

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Prions in skeletal muscles of deer with chronic wasting disease

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Creutzfeldt-Jakob disease and inclusion body myositis: abundant disease-associated prion protein in muscle

21 January 2018

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Prions in milk from ewes incubating natural scrapie

21 January 2018

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Coincident scrapie infection and nephritis lead to urinary prion excretion.

21 January 2018

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Bacterial colitis increases susceptibility to oral prion disease

21 January 2018

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Pathogenesis of prion diseases: current status and future outlook

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Urine from scrapie-infected hamsters comprises low levels of prion infectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Games played by rogue proteins in prion disorders and Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Novel proteinaceous infectious particles cause scrapie

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

NMR structure of the mouse prion protein domain PrP(121-231)

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

A general model of prion strains and their pathogenicity

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Insights into prion strains and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Extraneural prion neuroinvasion without lymphoreticular system infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Understanding the diversity of prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Measurement of the scrapie agent using an incubation time interval assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

A protease-resistant protein is a structural component of the scrapie prion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Regional mapping of prion proteins in brain

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Formation of native prions from minimal components in vitro

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Eight prion strains have PrP(Sc) molecules with different conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Physiology of the prion protein

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Cell biology. Prion toxicity: all sail and no anchor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Alzheimer's disease: A prion protein connection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Cellular isoform of the scrapie agent protein participates in lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Perturbation of T-cell development by insertional mutation of a PrP transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Cellular prion protein promotes Brucella infection into macrophages

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Dangerous liaisons between a microbe and the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Absence of evidence for the participation of the macrophage cellular prion protein in infection with Brucella suis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

The prion protein knockout mouse: a phenotype under challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Murine scrapie infection causes an abnormal germinal centre reaction in the spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Transmission of Creutzfeldt–Jakob disease with scrapie-like syndromes to mice

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Ionising radiation has no influence on scrapie incubation period in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Early and rapid engraftment of bone marrow-derived microglia in scrapie.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Complement facilitates early prion pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Pathogenesis of mouse scrapie: dynamics of vacuolation in brain and spinal cord after intraperitoneal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Assessing the involvement of migratory dendritic cells in the transfer of the scrapie agent from the immune to peripheral nervous systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Experimental transmission of sheep scrapie by intracerebral and oral routes to genetically susceptible Suffolk sheep in the United States.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Prion infection of muscle cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

A novel epitope for the specific detection of exogenous prion proteins in transgenic mice and transfected murine cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Prion strain discrimination in cell culture: the cell panel assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Accumulation of pathological prion protein PrPSc in the skin of animals with experimental and natural scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Antiprion immunotherapy: to suppress or to stimulate?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Postexposure prophylaxis against prion disease with a stimulator of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Prion pathogenesis in the absence of Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Immunoaffinity purification and neutralization of scrapie prion infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Immunization delays the onset of prion disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

In vitro propagation of the scrapie agent. I. Transformation of mouse glia and neuroblastoma cells after infection with the mouse-adapted scrapie strain c-506.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Characterization of scrapie infection in mouse neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Proteinase-resistant protein in human neuroblastoma cells infected with brain material from Creutzfeldt-Jakob patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Neural stem cell model for prion propagation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Evidence for the multiplication of scrapie agent in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Scrapie strains maintain biological phenotypes on propagation in a cell line in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Infection of a cell line of mouse L fibroblasts with scrapie agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Microglial cell line established from prion protein-overexpressing mice is susceptible to various murine prion strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

PrP expression and replication by Schwann cells: implications in prion spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Cultured peripheral neuroglial cells are highly permissive to sheep prion infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

A cell line infectible by prion strains from different species

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Packaging of prions into exosomes is associated with a novel pathway of PrP processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Incidence of Creutzfeldt-Jakob disease in Switzerland

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

PrPSc in mammary glands of sheep affected by scrapie and mastitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Chronic Lymphocytic Inflammation Specifies the Organ Tropism of Prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

PrP expression in B lymphocytes is not required for prion neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Germinal center B cells are dispensable in prion transport and neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Lymphotoxin-Dependent Prion Replication in Inflammatory Stromal Cells of Granulomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Cell biology: Infectious Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Turning off follicular dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.06.014

10.1016/J.FEBSLET.2009.06.014

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference