(Q37551896)

21 August 2017

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title

Epigenetic and microRNA-dependent control of cytochrome P450 expression: a gap between DNA and protein (English)

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21 August 2017

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Magnus Ingelman-Sundberg

series ordinal

2

object named as

Magnus Ingelman-Sundberg

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author name string

Alvin Gomez

series ordinal

1

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21 August 2017

publication date

1 July 2009

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21 August 2017

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21 August 2017

volume

10

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21 August 2017

issue

7

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21 August 2017

page(s)

1067-1076

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Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects

21 August 2017

cites work

1 reference

Cytochrome P450 pharmacogenetics and cancer.

21 January 2018

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Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy

21 January 2018

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A passion for P450s (rememberances of the early history of research on cytochrome P450).

21 January 2018

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Cytochrome P450s and other enzymes in drug metabolism and toxicity

21 January 2018

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Effects of genetic polymorphism of cytochrome P450 enzymes on the pharmacokinetics of benzodiazepines

21 January 2018

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Stability and flexibility of epigenetic gene regulation in mammalian development

21 January 2018

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Genomic DNA methylation: the mark and its mediators

21 January 2018

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The impact of chromatin in human cancer: linking DNA methylation to gene silencing

21 January 2018

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Role of chromatin/epigenetic modifications on DNA accessibility

21 January 2018

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Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies

21 January 2018

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Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

21 January 2018

1 reference

Epigenetics: a historical overview

21 January 2018

1 reference

An epigenetic role for noncoding RNAs and intragenic DNA methylation

21 January 2018

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Silencing by imprinted noncoding RNAs: is transcription the answer?

21 January 2018

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Non-coding RNAs: lost in translation?

21 January 2018

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21 January 2018

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Non–coding RNA genes and the modern RNA world

21 January 2018

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Monozygotic twins exhibit numerous epigenetic differences: clues to twin discordance?

21 January 2018

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Epigenetic differences arise during the lifetime of monozygotic twins

21 January 2018

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

21 January 2018

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The epigenetic basis of twin discordance in age-related diseases

21 January 2018

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21 January 2018

Epigenetics in cancer

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Developmental plasticity and human health.

21 January 2018

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Epigenetics and human disease

21 January 2018

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Epigenetics and complex disease: from etiology to new therapeutics

21 January 2018

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Persistent epigenetic differences associated with prenatal exposure to famine in humans

21 January 2018

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Epigenetic programming by maternal behavior

21 January 2018

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Environmental epigenomics and disease susceptibility

21 January 2018

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The DNA methyltransferases of mammals

21 January 2018

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

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DNA methylation: the nuts and bolts of repression

21 January 2018

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EUKARYOTIC CYTOSINE METHYLTRANSFERASES

21 January 2018

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Mammalian DNA (cytosine-5) methyltransferases and their expression

21 January 2018

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Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics

21 January 2018

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IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.

21 January 2018

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LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

21 January 2018

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Classification of colorectal cancer based on correlation of clinical, morphological and molecular features

21 January 2018

1 reference

Viral genome methylation as an epigenetic defense against geminiviruses

21 January 2018

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Epigenetic status of an adenovirus type 12 transgenome upon long-term cultivation in hamster cells

21 January 2018

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Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed hamster cells

21 January 2018

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DNA methylation, chromatin inheritance, and cancer

21 January 2018

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Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

21 January 2018

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Effects of DNA methylation on DNA-binding proteins and gene expression.

21 January 2018

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DNA methylation and chromatin structure: the puzzling CpG islands

21 January 2018

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DNA methylation affects the formation of active chromatin

21 January 2018

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DNA methylation precedes chromatin modifications under the influence of the strain-specific modifier Ssm1.

21 January 2018

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Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer

21 January 2018

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Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

21 January 2018

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The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol

21 January 2018

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Induction of cytochrome P4501A1.

21 January 2018

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Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas.

21 January 2018

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Enzymatic activities of human lung tissue: relationship with smoking habits

21 January 2018

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Ligand binding and activation of the Ah receptor

21 January 2018

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Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1.

21 January 2018

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Functional role of AhR in the expression of toxic effects by TCDD

21 January 2018

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Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer

21 January 2018

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Variation in CYP1A2 activity and its clinical implications: influence of environmental factors and genetic polymorphisms

21 January 2018

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21 January 2018

CpG islands and genes

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The role of DNA methylation in mammalian epigenetics

21 January 2018

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CpG islands as gene markers in the human genome.

21 January 2018

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CpG islands in vertebrate genomes

21 January 2018

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Comprehensive analysis of CpG islands in human chromosomes 21 and 22

21 January 2018

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Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers

21 January 2018

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Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

21 January 2018

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Expression of CYP2W1 in colon tumors: regulation by gene methylation.

21 January 2018

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Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase

21 January 2018

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Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples

21 January 2018

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Expression of CYP2E1 in human lung and kidney during development and in full-term placenta: a differential methylation of the gene is involved in the regulation process.

21 January 2018

1 reference

Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

1 reference

The controversial 30 nm chromatin fibre

21 January 2018

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Crystal structure of the nucleosome core particle at 2.8 A resolution

21 January 2018

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Genome-wide approaches to studying chromatin modifications

21 January 2018

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The language of covalent histone modifications

21 January 2018

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M phase-specific phosphorylation of histone H1.5 at threonine 10 by GSK-3.

21 January 2018

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Histone ubiquitination associates with BRCA1-dependent DNA damage response

21 January 2018

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Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications

21 January 2018

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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.

21 January 2018

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Chromatin-remodelling mechanisms in cancer.

21 January 2018

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How does the histone code work?

21 January 2018

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Translating the Histone Code

21 January 2018

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HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation

21 January 2018

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Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin.

21 January 2018

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Dynamic patterns of histone methylation are associated with ontogenic expression of the Cyp3a genes during mouse liver maturation

21 January 2018

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The functions of animal microRNAs

21 January 2018

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MicroRNA function in animal development

21 January 2018

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MicroRNA regulates the expression of human cytochrome P450 1B1.

21 January 2018

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Differential expression of microRNAs in early-stage neoplastic transformation in the lungs of F344 rats chronically treated with the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

21 January 2018

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MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium

21 January 2018

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CYP3A4 and pregnane X receptor humanized mice

21 January 2018

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Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.

21 January 2018

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A nuclear receptor system constituted by RAR and RXR induces aromatase activity in MCF-7 human breast cancer cells

21 January 2018

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Hypermethylation of the retinoic acid receptor-beta(2) gene in head and neck carcinogenesis.

21 January 2018

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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells

21 January 2018

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Cytochrome P450-mediated metabolism of estrogens and its regulation in human.

21 January 2018

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Epigenetic regulation of the estrogen receptor alpha promoter in the cerebral cortex following ischemia in male and female rats

21 January 2018

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Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/PGS.09.56

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21 August 2017

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