(Q37565671)

21 August 2017

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title

Relevance of the aryl hydrocarbon receptor (AhR) for clinical toxicology (English)

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21 August 2017

Tracey D Bradshaw

1

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21 August 2017

David R Bell

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

1 August 2009

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21 August 2017

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21 August 2017

volume

47

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21 August 2017

issue

7

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21 August 2017

page(s)

632-642

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Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

21 August 2017

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cDNA cloning and structure of mouse putative Ah receptor

21 January 2018

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Human arylhydrocarbon receptor: functional expression and chromosomal assignment to 7p21.

21 January 2018

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

21 January 2018

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Heat shock protein hsp90 regulates dioxin receptor function in vivo

21 January 2018

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A hypomorphic allele of aryl hydrocarbon receptor-associated protein-9 produces a phenocopy of the AHR-null mouse

21 January 2018

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The aryl hydrocarbon (Ah) receptor transcriptional regulator hepatitis B virus X-associated protein 2 antagonizes p23 binding to Ah receptor-Hsp90 complexes and is dispensable for receptor function

21 January 2018

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Recombinant expression of aryl hydrocarbon receptor for quantitative ligand-binding analysis

21 January 2018

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Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide

21 January 2018

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Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice

21 January 2018

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Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity.

21 January 2018

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Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA-binding domain of the aryl hydrocarbon receptor.

21 January 2018

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Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer

21 January 2018

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Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes

21 January 2018

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Polymorphisms in the human AH receptor

21 January 2018

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Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: clinical and laboratory effects

21 January 2018

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2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

21 January 2018

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https://api.crossref.org/works/10.1080%2F15563650903140423

Photocontact dermatitis and chloracne: two major occupational and environmental skin diseases induced by different actions of halogenated chemicals

21 January 2018

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Blood lipid concentrations of dioxins and dibenzofurans causing chloracne

21 January 2018

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Severe halogen acne due to a trifluoromethylpyrazole derivative and its resistance to isotretinoin.

21 January 2018

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Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. I: No decrease in epididymal sperm count after a single acute dose

21 January 2018

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A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans Hooded rat offspring

21 January 2018

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In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs prostate development. 1. Effects on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. II: Chronic dosing causes developmental delay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

A truncation in the aryl hydrocarbon receptor of the CRL:WI(Han) rat does not affect the developmental toxicity of TCDD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Developmental toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the most TCDD-resistant and -susceptible rat strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Retention and excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin by rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Relationships between tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs, and toxicity in the developing male Wistar(Han) rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Half-lives of tetra-, penta-, hexa-, hepta-, and octachlorodibenzo-p-dioxin in rats, monkeys, and humans--a critical review

21 January 2018

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https://api.crossref.org/works/10.1080%2F15563650903140423

Concentration-dependent TCDD elimination kinetics in humans: toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and congeners in infants. A toxicokinetic model of human lifetime body burden by TCDD with special emphasis on its uptake by nutrition.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15563650903140423

Age- and concentration-dependent elimination half-life of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Seveso children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein - The role of hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The Caenorhabditis elegans aryl hydrocarbon receptor, AHR-1, regulates neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The AHR-1 aryl hydrocarbon receptor and its co-factor the AHA-1 aryl hydrocarbon receptor nuclear translocator specify GABAergic neuron cell fate in C. elegans.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15563650903140423

The Caenorhabditis elegans AHR-1 transcription complex controls expression of soluble guanylate cyclase genes in the URX neurons and regulates aggregation behavior

21 January 2018

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https://api.crossref.org/works/10.1080%2F15563650903140423

The murine Cyp1a1 gene is expressed in a restricted spatial and temporal pattern during embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse

21 January 2018

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https://api.crossref.org/works/10.1080%2F15563650903140423

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The immune phenotype of AhR null mouse mutants: not a simple mirror of xenobiotic receptor over-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Species comparison in P450 induction: effects of dexamethasone, omeprazole, and rifampin on P450 isoforms 1A and 3A in primary cultured hepatocytes from man, Sprague-Dawley rat, minipig, and beagle dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Clinical pharmacology of proton pump inhibitors: what the practising physician needs to know

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Inhibition of drug metabolism in human liver microsomes by nizatidine, cimetidine and omeprazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Omeprazole alleviates benzo[a]pyrene cytotoxicity by inhibition of CYP1A1 activity in human and mouse hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The p53 inhibitor pifithrin-alpha is a potent agonist of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Methyl-substituted diindolylmethanes as inhibitors of estrogen-induced growth of T47D cells and mammary tumors in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Interaction of the aryl hydrocarbon receptor ligand 6-methyl-1,3,8-trichlorodibenzofuran with estrogen receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8-trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Interference of glucocorticoids with apoptosis signaling and host-tumor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Activation of aminoflavone (NSC 686288) by a sulfotransferase is required for the antiproliferative effect of the drug and for induction of histone gamma-H2AX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Toxic and chemopreventive ligands preferentially activate distinct aryl hydrocarbon receptor pathways: implications for cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Activation of the Ah receptor signaling pathway by prostaglandins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Endogenous functions of the aryl hydrocarbon receptor (AHR): intersection of cytochrome P450 1 (CYP1)-metabolized eicosanoids and AHR biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Aspartate aminotransferase generates proagonists of the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

The aryl hydrocarbon receptor and light

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15563650903140423

Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro

21 January 2018

1 reference

31 May 2024

https://opencitations.net/index/api/v1/citations/10.1124/MOL.106.032748

Identifiers

DOI

10.1080/15563650903140423

1 reference

21 August 2017

1 reference