(Q37575114)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

review article

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title

Physical inactivity and obesity: links with insulin resistance and type 2 diabetes mellitus (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

0 references

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1 reference

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

author name string

Asker E Jeukendrup

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

publication date

1 September 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

Diabetes - Metabolism: Research and Reviews

4 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

volume

25 Suppl 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

page(s)

S18-23

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19662619%20AND%20SRC:MED&resulttype=core&format=json

Prospective study of risk factors for development of non-insulin dependent diabetes in middle aged British men.

4 February 2020

cites work

1 reference

Skeletal muscle lipid metabolism with obesity

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PKC-theta knockout mice are protected from fat-induced insulin resistance

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Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

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The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

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Reduced capacity and affinity of skeletal muscle for insulin-mediated glucose uptake in noninsulin-dependent diabetic subjects. Effects of insulin therapy

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Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats

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7 January 2021

Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36.

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7 January 2021

Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss

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7 January 2021

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

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7 January 2021

Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats

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7 January 2021

Skeletal muscle utilization of free fatty acids in women with visceral obesity

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7 January 2021

Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus

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7 January 2021

Lipid oxidation is reduced in obese human skeletal muscle

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7 January 2021

Substrate utilization during exercise in formerly morbidly obese women.

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7 January 2021

Impaired plasma fatty acid oxidation in extremely obese women

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7 January 2021

Intramuscular lipid content is increased in obesity and decreased by weight loss

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7 January 2021

Fat content in individual muscle fibers of lean and obese subjects

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7 January 2021

Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes

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7 January 2021

Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat.

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7 January 2021

Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

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7 January 2021

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

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7 January 2021

Skeletal muscle triglyceride levels are inversely related to insulin action.

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7 January 2021

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

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7 January 2021

Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects.

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7 January 2021

Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women

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7 January 2021

Effects of weight loss on regional fat distribution and insulin sensitivity in obesity

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7 January 2021

Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid

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7 January 2021

Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity

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7 January 2021

Exercise training increases intramyocellular lipid and oxidative capacity in older adults

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7 January 2021

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

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7 January 2021

Dose-response effect of elevated plasma free fatty acid on insulin signaling

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7 January 2021

Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity

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7 January 2021

Peroxisome proliferator-activated receptor-gamma coactivator-1 and insulin resistance: acute effect of fatty acids.

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7 January 2021

Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes

1 reference

7 January 2021

Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes.

1 reference

7 January 2021

Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects.

1 reference

7 January 2021

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

7 January 2021

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

7 January 2021

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

7 January 2021

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

7 January 2021

Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.

1 reference

7 January 2021

Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cdelta

1 reference

7 January 2021

Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

1 reference

7 January 2021

Protein kinase C modulates insulin action in human skeletal muscle

1 reference

7 January 2021

Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation

1 reference

7 January 2021

Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism

1 reference

7 January 2021

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

1 reference

7 January 2021