(Q37577150)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

Triazoles inhibit cholesterol export from lysosomes by binding to NPC1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Feiran Lu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

author name string

Xiaochun Li

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Akash Das

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Qiren Liang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jef K De Brabander

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Michael S Brown

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Joseph L Goldstein

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

language of work or name

English

0 references

publication date

19 December 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

30 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

page(s)

89-94

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

30 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5224357/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2.

1 reference

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Structure of human Niemann-Pick C1 protein

23 August 2017

1 reference

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Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis

23 August 2017

1 reference

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Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin

23 August 2017

1 reference

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Use of mutant 125I-perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

23 August 2017

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NIH Image to ImageJ: 25 years of image analysis

23 August 2017

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Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Cholesterol trafficking is required for mTOR activation in endothelial cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Reviews of anti-infective agents: posaconazole: a broad-spectrum triazole antifungal agent

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

The Strep-tag system for one-step purification and high-affinity detection or capturing of proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Niemann-Pick C research from mouse to gene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Commentary. Lysosomotropic agents

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

A receptor-mediated pathway for cholesterol homeostasis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5224357

Triazole antifungals: a review

23 August 2017

1 reference

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Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop

6 September 2017

1 reference

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Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

6 September 2017

1 reference

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Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells.

25 June 2018

2 references

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25 June 2018

19 October 2022

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Pharmacological inhibition of the intracellular transport of low-density lipoprotein-derived cholesterol in Chinese hamster ovary cells

1 reference

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A 25-hydroxycholesterol-resistant cell line deficient in acyl-CoA: cholesterol acyltransferase

25 June 2018

1 reference

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The transport of low density lipoprotein-derived cholesterol to the plasma membrane is defective in NPC1 cells

25 June 2018

1 reference

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Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1619571114

Ventromedial hypothalamic neurons control a defensive emotion state.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1619571114

Cholesterol trafficking and distribution

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27994139

12 December 2020

inferred from PubMed ID database lookup

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27994139

12 December 2020

inferred from PubMed ID database lookup

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27994139

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1619571114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994139%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

PubMed publication ID

27994139

1 reference