(Q37577611)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19669606%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

review article

1 reference

title

Interaction between alpha-synuclein and metal ions, still looking for a role in the pathogenesis of Parkinson's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19669606%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

1 reference

1 reference

2

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5 February 2020

Luigi Bubacco

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19669606%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

3

Stefano Mammi

1 reference

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5 February 2020

1

Marco Bisaglia

1 reference

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5 February 2020

publication date

1 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19669606%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

published in

NeuroMolecular Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19669606%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

11

1 reference

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5 February 2020

issue

4

1 reference

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5 February 2020

page(s)

239-251

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https://scigraph.springernature.com/pub.10.1007/s12017-009-8082-1

5 February 2020

exact match

0 references

cites work

The cellular prion protein binds copper in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS12017-009-8082-1

Redox imbalance in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12017-009-8082-1

NMR mapping of copper binding sites in alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12017-009-8082-1

A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12017-009-8082-1

Localization of phosphoneuroprotein 14 (PNP 14) and its mRNA expression in rat brain determined by immunocytochemistry and in situ hybridization

21 January 2018

1 reference

12 December 2020

Structure and dynamics of micelle-bound human alpha-synuclein

1 reference

12 December 2020

Identification of the region of non-Abeta component (NAC) of Alzheimer's disease amyloid responsible for its aggregation and toxicity

1 reference

12 December 2020

Investigation of alpha-synuclein fibril structure by site-directed spin labeling

1 reference

12 December 2020

The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function

1 reference

12 December 2020

alpha-Synuclein and neuronal cell death

1 reference

12 December 2020

A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles.

1 reference

12 December 2020

Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments

1 reference

12 December 2020

Structural organization of alpha-synuclein fibrils studied by site-directed spin labeling

1 reference

12 December 2020

The 11-mer repeats of human alpha-synuclein in vesicle interactions and lipid composition discrimination: a cooperative role

1 reference

12 December 2020

Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

1 reference

12 December 2020

Occupational and environmental risk factors for Parkinson's disease

1 reference

12 December 2020

Function and regulation of transferrin and ferritin.

1 reference

12 December 2020

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers

1 reference

12 December 2020

Opinion: What is the role of protein aggregation in neurodegeneration?

1 reference

12 December 2020

Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure

1 reference

12 December 2020

Unique copper-induced oligomers mediate alpha-synuclein toxicity

1 reference

12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

1 reference

12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

12 December 2020

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

1 reference

12 December 2020

Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030.

1 reference

12 December 2020

Phosphorylation of a vesicular monoamine transporter by casein kinase II.

1 reference

12 December 2020

Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein

1 reference

12 December 2020

Structural insights on physiological functions and pathological effects of alpha-synuclein.

1 reference

12 December 2020

Raised cerebrospinal-fluid copper concentration in Parkinson's disease

1 reference

12 December 2020

Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

1 reference

12 December 2020

A role for alpha-synuclein in the regulation of dopamine biosynthesis

1 reference

12 December 2020

Conformational properties of alpha-synuclein in its free and lipid-associated states

1 reference

12 December 2020

Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

1 reference

12 December 2020

Products of Cu(II)-catalyzed oxidation of the N-terminal fragments of alpha-synuclein in the presence of hydrogen peroxide.

1 reference

12 December 2020

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein

1 reference

12 December 2020

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

1 reference

12 December 2020

Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease

1 reference

12 December 2020

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

1 reference

12 December 2020

The 5'-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element

1 reference

12 December 2020

Site-specific interactions of Cu(II) with alpha and beta-synuclein: bridging the molecular gap between metal binding and aggregation

1 reference

12 December 2020

Nature of inhibition of mitochondrial respiratory complex I by 6-Hydroxydopamine

1 reference

12 December 2020

The cellular prion protein binds copper in vivo

1 reference

12 December 2020

1 reference

12 December 2020

Neurodegenerative disease: amyloid pores from pathogenic mutations.

1 reference

12 December 2020

Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress

1 reference

12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

12 December 2020

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

12 December 2020

Cu2+Binding Modes of Recombinant α-Synuclein − Insights from EPR Spectroscopy

1 reference

12 December 2020

Thermodynamics imprinting reveals differential binding of metals to α-synuclein: Relevance to parkinson’s disease

1 reference

12 December 2020

Binding of Cu(II) to human alpha-synucleins: comparison of wild type and the point mutations associated with the familial Parkinson's disease

1 reference

12 December 2020

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1 reference

12 December 2020

Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein

1 reference

12 December 2020

Metal-catalyzed oxidation of alpha-synuclein in the presence of Copper(II) and hydrogen peroxide.

1 reference

12 December 2020

The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service

1 reference

12 December 2020

Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

1 reference

12 December 2020

Interaction of α-Synuclein with Divalent Metal Ions Reveals Key Differences: A Link between Structure, Binding Specificity and Fibrillation Enhancement

1 reference

12 December 2020

Copper(II)-induced self-oligomerization of alpha-synuclein.

1 reference

12 December 2020

Lipid interaction of alpha-synuclein during the metal-catalyzed oxidation in the presence of Cu2+ and H2O2.

1 reference

12 December 2020

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

1 reference

12 December 2020

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

12 December 2020

Conformational equilibria in monomeric alpha-synuclein at the single-molecule level

1 reference

12 December 2020

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro

1 reference

12 December 2020

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

1 reference

12 December 2020

Effects of nitration on the structure and aggregation of alpha-synuclein

1 reference

12 December 2020

Copper (Cu2+) induces degeneration of dopaminergic neurons in the nigrostriatal system of rats

1 reference

12 December 2020

1 reference

12 December 2020

Iron in brain function and dysfunction with emphasis on Parkinson's disease

1 reference

12 December 2020

Parkinson's disease: from monogenic forms to genetic susceptibility factors

1 reference

12 December 2020

Methionine oxidation inhibits fibrillation of human alpha-synuclein in vitro

1 reference

12 December 2020

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

1 reference

12 December 2020

Certain Metals Trigger Fibrillation of Methionine-oxidized α-Synuclein

1 reference

12 December 2020

Alpha-synuclein in Lewy bodies

1 reference

12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

12 December 2020

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis

1 reference

12 December 2020

Iron and paraquat as synergistic environmental risk factors in sporadic Parkinson's disease accelerate age-related neurodegeneration.

1 reference

12 December 2020

Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations.

1 reference

12 December 2020

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

1 reference

12 December 2020

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

1 reference

12 December 2020

alpha-Synuclein is phosphorylated in synucleinopathy lesions

1 reference

12 December 2020

RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport.

1 reference

12 December 2020

Copper(II) binding by fragments of alpha-synuclein containing M1-D2- and -H50-residues; a combined potentiometric and spectroscopic study

1 reference

12 December 2020

Synucleins are a novel class of substrates for G protein-coupled receptor kinases

1 reference

12 December 2020

Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system

1 reference

12 December 2020

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

1 reference

12 December 2020

Cytotoxic and genotoxic potential of dopamine

1 reference

12 December 2020

Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism.

1 reference

12 December 2020

Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes.

1 reference

12 December 2020

The aggregation and fibrillation of alpha-synuclein

1 reference

12 December 2020

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

1 reference

12 December 2020

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

1 reference

12 December 2020

1 reference

12 December 2020

Role of alpha-synuclein in presynaptic dopamine recruitment.

1 reference

12 December 2020

Evidence for a partially folded intermediate in alpha-synuclein fibril formation

1 reference

12 December 2020

Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

1 reference

12 December 2020

The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging

1 reference

12 December 2020

The fold of alpha-synuclein fibrils

1 reference

12 December 2020

Phosphorylation-dependent metal binding by α-synuclein peptide fragments

1 reference

12 December 2020

Copper(II) binding to alpha-synuclein, the Parkinson's protein

1 reference

12 December 2020

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies

1 reference

12 December 2020