(Q37585309)

21 August 2017

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title

Hereditary ovarian cancer: biology, response to chemotherapy and prognosis (English)

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21 August 2017

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Tamar Safra

1

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21 August 2017

language of work or name

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1 September 2009

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21 August 2017

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21 August 2017

volume

5

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21 August 2017

issue

5

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21 August 2017

page(s)

543-553

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Cell cycle control and cancer

21 August 2017

cites work

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21 January 2018

Cancer statistics, 2006

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Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer

21 January 2018

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Population attributes affecting the prevalence of BRCA mutation carriers in epithelial ovarian cancer cases in israel

21 January 2018

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Parity, Oral Contraceptives, and the Risk of Ovarian Cancer among Carriers and Noncarriers of aBRCA1orBRCA2Mutation

21 January 2018

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Cancer risks among BRCA1 and BRCA2 mutation carriers

21 January 2018

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Improved survival in women with BRCA-associated ovarian carcinoma

21 January 2018

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Survival of BRCA1 breast and ovarian cancer patients: a population-based study from southern Sweden

21 January 2018

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Improved survival in BRCA2 carriers with ovarian cancer

21 January 2018

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TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival

21 January 2018

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Survival analysis in familial ovarian cancer, a case control study

21 January 2018

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The prevalence of common BRCA1 and BRCA2 mutations among Ashkenazi Jews

21 January 2018

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Evidence of founder mutations in Finnish BRCA1 and BRCA2 families

21 January 2018

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Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families

21 January 2018

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Founder mutations in the BRCA1 gene in Polish families with breast-ovarian cancer

21 January 2018

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Multiplex SNaPshot for detection of BRCA1/2 common mutations in Spanish and Spanish related breast/ovarian cancer families

21 January 2018

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The frequency of founder mutations in the BRCA1, BRCA2, and APC genes in Australian Ashkenazi Jews: implications for the generality of U.S. population data

21 January 2018

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BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer

21 January 2018

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Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals

21 January 2018

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Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis

21 January 2018

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Mutation and cancer: statistical study of retinoblastoma

21 January 2018

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Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2

21 January 2018

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

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The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals

21 January 2018

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Identification of the breast cancer susceptibility gene BRCA2

21 January 2018

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Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer

21 January 2018

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BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

21 January 2018

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Cancer-susceptibility genes. Gatekeepers and caretakers

21 January 2018

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THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

21 January 2018

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Breast cancer genetics: what we know and what we need

21 January 2018

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The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

21 January 2018

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Molecular mechanisms of DNA double strand break repair

21 January 2018

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Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment

21 January 2018

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Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

21 January 2018

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Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

21 January 2018

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Cancer susceptibility and the functions of BRCA1 and BRCA2

21 January 2018

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Tracing the network connecting BRCA and Fanconi anaemia proteins

21 January 2018

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Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

21 January 2018

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Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

21 January 2018

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Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

21 January 2018

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RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

21 January 2018

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Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

21 January 2018

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Association of BRCA1 with Rad51 in mitotic and meiotic cells

21 January 2018

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Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

21 January 2018

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Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations

21 January 2018

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Molecular views of recombination proteins and their control

21 January 2018

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Involvement of Brca2 in DNA repair

21 January 2018

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A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

21 January 2018

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BRCA1 and BRCA2: chemosensitivity, treatment outcomes and prognosis

21 January 2018

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BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy

21 January 2018

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BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

21 January 2018

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Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway

21 January 2018

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Brca1 controls homology-directed DNA repair

21 January 2018

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Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS.

21 January 2018

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A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer

21 January 2018

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Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy.

21 January 2018

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BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents

21 January 2018

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BRCA1 downregulation leads to premature inactivation of spindle checkpoint and confers paclitaxel resistance

21 January 2018

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Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

21 January 2018

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Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions

21 January 2018

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Secondary BRCA1 and BRCA2 alterations and acquired chemoresistance

21 January 2018

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Strand breaks arising from the repair of the 5-bromodeoxyuridine-substituted template and methyl methanesulphonate-induced lesions can explain the formation of sister chromatid exchanges.

21 January 2018

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Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination

21 January 2018

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“BRCAness” Syndrome in Ovarian Cancer: A Case-Control Study Describing the Clinical Features and Outcome of Patients With Epithelial Ovarian Cancer Associated WithBRCA1andBRCA2Mutations

21 January 2018

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Cancer Risk Estimates for BRCA1 Mutation Carriers Identified in a Risk Evaluation Program

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/WHE.09.40

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21 August 2017

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