(Q37593435)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

review article

1 reference

title

Therapy of chronic myeloid leukemia: twilight of the imatinib era? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

main subject

chronic myeloid leukemia

0 references

1 reference

1 reference

Sylwester Glowacki

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

publication date

30 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

page(s)

596483

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

10 March 2020

copyright license

start time

30 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to ponatinib

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Enhanced and selective killing of chronic myelogenous leukemia cells with an engineered BCR-ABL binding protein and imatinib

23 August 2017

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Epigenomics of leukemia: from mechanisms to therapeutic applications

23 August 2017

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Recent advances in the path toward the cure for chronic myeloid leukemia

23 August 2017

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Transcription suppression of SARI (suppressor of AP-1, regulated by IFN) by BCR-ABL in human leukemia cells

23 August 2017

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cml biology for the clinician in 2011: six impossible things to believe before breakfast on the way to cure.

23 August 2017

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Advances in the treatment of chronic myeloid leukemia

23 August 2017

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Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia

23 August 2017

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Recent advances in apoptosis, mitochondria and drug resistance in cancer cells

23 August 2017

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First-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib

23 August 2017

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Chronic myeloid leukemia therapy in the era of tyrosine kinase inhibitors--the first molecular targeted treatment

23 August 2017

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Chronic myeloid leukemia: mechanisms of blastic transformation

23 August 2017

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Chronic myelogenous leukemia: treatment and monitoring

23 August 2017

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Long-term outcome of patients with chronic myeloid leukemia treated with second-generation tyrosine kinase inhibitors after imatinib failure is predicted by the in vitro sensitivity of BCR-ABL kinase domain mutations

23 August 2017

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Predictors of primary imatinib resistance in chronic myelogenous leukemia are distinct from those in secondary imatinib resistance

23 August 2017

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Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

23 August 2017

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Novel agents in CML therapy: tyrosine kinase inhibitors and beyond

23 August 2017

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Translation of the Philadelphia chromosome into therapy for CML.

23 August 2017

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Molecular biology of bcr-abl1-positive chronic myeloid leukemia

23 August 2017

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Therapeutic options for chronic myeloid leukemia: focus on imatinib (Glivec, Gleevectrade mark).

23 August 2017

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Emerging stem cell concepts for imatinib-resistant chronic myeloid leukaemia: implications for the biology, management, and therapy of the disease.

23 August 2017

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Therapy options in imatinib failures

23 August 2017

1 reference

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SGX393 inhibits the CML mutant Bcr-AblT315I and preempts in vitro resistance when combined with nilotinib or dasatinib.

23 August 2017

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Part II: management of resistance to imatinib in chronic myeloid leukaemia

23 August 2017

1 reference

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Part I: mechanisms of resistance to imatinib in chronic myeloid leukaemia

23 August 2017

1 reference

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Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Gene silencing by DNA methylation in haematological malignancies

23 August 2017

1 reference

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Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

23 August 2017

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Defining and managing imatinib resistance

23 August 2017

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Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

23 August 2017

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Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

23 August 2017

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Active transport of imatinib into and out of cells: implications for drug resistance

23 August 2017

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Overriding imatinib resistance with a novel ABL kinase inhibitor

23 August 2017

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Imatinib therapy in chronic myelogenous leukemia: strategies to avoid and overcome resistance

23 August 2017

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Molecular mechanisms of resistance of leukemia to imatinib mesylate

23 August 2017

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The biology of CML blast crisis

23 August 2017

1 reference

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Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg

23 August 2017

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Chronic Myeloid Leukemia — Advances in Biology and New Approaches to Treatment

23 August 2017

1 reference

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Chronic myelogenous leukemia: the news you have and haven't heard

23 August 2017

1 reference

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Chronic Myelogenous Leukemia: Disease Biology and Current and Future Therapeutic Strategies.

23 August 2017

1 reference

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STI571: targeting BCR-ABL as therapy for CML.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Chronic myeloid leukemia: overview of new agents and comparative analysis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Ponatinib (AP24534) is a novel potent inhibitor of oncogenic RET mutants associated with thyroid cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Why imatinib remains an exception of cancer research

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

New insights into the pathogenesis of chronic myeloid leukaemia: towards a path to cure.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

A genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Activity of the Aurora kinase inhibitor VX-680 against Bcr/Abl-positive acute lymphoblastic leukemias

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Pharmacogenomic analysis of cytogenetic response in chronic myeloid leukemia patients treated with imatinib

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Mechanism of resistance to the ABL tyrosine kinase inhibitor STI571 in BCR/ABL-transformed hematopoietic cell lines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Three novel patient-derived BCR/ABL mutants show different sensitivity to second and third generation tyrosine kinase inhibitors.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Imatinib in chronic myeloid leukemia elderly patients

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

New developments in tyrosine kinase inhibitor therapy for newly diagnosed chronic myeloid leukemia

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Mechanisms of Resistance to Imatinib and Second-Generation Tyrosine Inhibitors in Chronic Myeloid Leukemia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Dasatinib in the treatment of imatinib refractory chronic myeloid leukemia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Combined Abl inhibitor therapy for minimizing drug resistance in chronic myeloid leukemia: Src/Abl inhibitors are compatible with imatinib

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

hOCT 1 and resistance to imatinib

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

In chronic myeloid leukemia white cells from cytogenetic responders and non-responders to imatinib have very similar gene expression signatures.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Imatinib (ST1571) provides only limited selectivity for CML cells and treatment might be complicated by silent BCR-ABL genes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Roots of clinical resistance to STI-571 cancer therapy

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

ABL1 methylation is a distinct molecular event associated with clonal evolution of chronic myeloid leukemia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929284

Thrombopoiesis: new ITP paradigm?

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2014%2F596483

Identification of genes involved in imatinib resistance in CML: a gene-expression profiling approach

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2014%2F596483

Cotreatment with vorinostat (suberoylanilide hydroxamic acid) enhances activity of dasatinib (BMS-354825) against imatinib mesylate-sensitive or imatinib mesylate-resistant chronic myelogenous leukemia cells

21 January 2018

1 reference

12 December 2020

DNA CONTENTS OF CHROMOSOME PH1 AND CHROMOSOME 21 IN HUMAN CHRONIC GRANULOCYTIC LEUKEMIA

1 reference

12 December 2020

Chronic myelogenous leukemia

1 reference

12 December 2020

Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/596483

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

24634785

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24634785%20AND%20SRC:MED&resulttype=core&format=json