(Q37604024)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

Michele Francesco Maria Sciacca

3 March 2020

author

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Jeffrey Brender

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Ayyalusamy Ramamoorthy

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Jie Zheng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Jun Zhao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Rundong Hu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Hong Chen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

language of work or name

English

0 references

publication date

1 February 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

number of pages

10

1 reference

Physical Chemistry Chemical Physics

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

16

1 reference

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3 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

2368-2377

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

All-atom empirical potential for molecular modeling and dynamics studies of proteins

3 March 2020

cites work

1 reference

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Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP.

23 August 2017

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Probing ion channel activity of human islet amyloid polypeptide (amylin).

23 August 2017

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The toxicity of amyloid β oligomers

23 August 2017

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Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions

23 August 2017

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Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology

23 August 2017

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Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective

23 August 2017

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Polymorphic structures of Alzheimer's β-amyloid globulomers.

23 August 2017

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Interactions of Aβ25-35 β-barrel-like oligomers with anionic lipid bilayer and resulting membrane leakage: an all-atom molecular dynamics study

23 August 2017

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β-Barrel topology of Alzheimer's β-amyloid ion channels

23 August 2017

1 reference

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Amyloidogenic protein-membrane interactions: mechanistic insight from model systems

23 August 2017

1 reference

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Structural convergence among diverse, toxic beta-sheet ion channels

23 August 2017

1 reference

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Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

23 August 2017

1 reference

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Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels

23 August 2017

1 reference

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K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis

23 August 2017

1 reference

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Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide

23 August 2017

1 reference

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Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935214

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

23 August 2017

1 reference

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New structures help the modeling of toxic amyloidbeta ion channels

23 August 2017

1 reference

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Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.

23 August 2017

1 reference

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Membrane fragmentation by an amyloidogenic fragment of human Islet Amyloid Polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes

23 August 2017

1 reference

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Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process

23 August 2017

1 reference

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Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

23 August 2017

1 reference

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Amyloid ion channels: a common structural link for protein-misfolding disease

23 August 2017

1 reference

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Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

23 August 2017

1 reference

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Structure and fluctuations of charged phosphatidylserine bilayers in the absence of salt

23 August 2017

1 reference

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Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

23 August 2017

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Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis

23 August 2017

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Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide

23 August 2017

1 reference

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Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

23 August 2017

1 reference

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Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

23 August 2017

1 reference

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The pancreatic islet cells in insular amyloidosis in human diabetic and non-diabetic adults.

23 August 2017

1 reference

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Secretion of islet amyloid polypeptide in response to glucose

25 June 2018

1 reference

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pH-dependent conformational ensemble and polymorphism of amyloid-β core fragment

25 June 2018

1 reference

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Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations

1 September 2018

1 reference

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Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: a coarse-grained molecular dynamics study.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935214

Structural polymorphism of human islet amyloid polypeptide (hIAPP) oligomers highlights the importance of interfacial residue interactions.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935214

Pore formation by beta-2-microglobulin: a mechanism for the pathogenesis of dialysis associated amyloidosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935214

Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC3CP53345J

Heterogeneous triangular structures of human islet amyloid polypeptide (amylin) with internal hydrophobic cavity and external wrapping morphology reveal the polymorphic nature of amyloid fibrils

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3935214

Water, proton, and ion transport: from nanotubes to proteins

2 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC3CP53345J

Comparative Molecular Dynamics Study of Human Islet Amyloid Polypeptide (IAPP) and Rat IAPP Oligomers

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC3CP53345J

Pore formation by the cytotoxic islet amyloid peptide amylin

21 January 2018

1 reference

12 December 2020

Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers

1 reference

12 December 2020

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

1 reference

12 December 2020

[Amyloid of islets of Langerhans and its relation to diabetes mellitus (author's transl)]

1 reference

12 December 2020

Identifiers

DOI

10.1039/C3CP53345J

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

24352606

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352606%20AND%20SRC:MED&resulttype=core&format=json