(Q52619646)

English

Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: a coarse-grained molecular dynamics study.

scientific article published on 29 November 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: a coarse-grained molecular dynamics study. (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

2

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

object named as

Haibin Su

3

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author name string

Weixin Xu

1

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

Lars Nordenskiöld

4

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

Yuguang Mu

5

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Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

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publication date

29 November 2011

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Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

Physical Review E

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Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

84

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Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

5 Pt 1

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

051922

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

Conformational disease

1 reference

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21 January 2018

Protein misfolding and disease: from the test tube to the organism

1 reference

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21 January 2018

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

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21 January 2018

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

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21 January 2018

Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide.

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

1 reference

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21 January 2018

Membrane interaction of islet amyloid polypeptide

1 reference

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21 January 2018

Neurodegenerative disease: amyloid pores from pathogenic mutations.

1 reference

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21 January 2018

Amyloid ion channels: a common structural link for protein-misfolding disease

1 reference

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21 January 2018

Structure of alpha-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding

1 reference

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21 January 2018

Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process

1 reference

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21 January 2018

New structures help the modeling of toxic amyloidbeta ion channels

1 reference

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21 January 2018

Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer

1 reference

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21 January 2018

Raft lipids as common components of human extracellular amyloid fibrils

1 reference

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21 January 2018

Prion rods contain small amounts of two host sphingolipids as revealed by thin-layer chromatography and mass spectrometry

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21 January 2018

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

1 reference

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21 January 2018

Phospholipid catalysis of diabetic amyloid assembly

1 reference

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21 January 2018

Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form

1 reference

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21 January 2018

Membrane permeabilization by Islet Amyloid Polypeptide

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

1 reference

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21 January 2018

The N-terminal fragment of human islet amyloid polypeptide is non-fibrillogenic in the presence of membranes and does not cause leakage of bilayers of physiologically relevant lipid composition

1 reference

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21 January 2018

Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Cholesterol in islet dysfunction and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Molecular dynamics simulations of phospholipid bilayers with cholesterol

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Thermomechanical and transition properties of dimyristoylphosphatidylcholine/cholesterol bilayers

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Interaction between Alzheimer's Abeta(25-35) peptide and phospholipid bilayers: the role of cholesterol.

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Cholesterol regulates assembly of human islet amyloid polypeptide on model membranes

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Melittin-lipid bilayer interactions and the role of cholesterol

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Assembly dynamics of two-beta sheets revealed by molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Membrane simulations: bigger and better?

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Interaction of protegrin-1 with lipid bilayers: membrane thinning effect

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Coarse-grained model for phospholipid/cholesterol bilayer

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Transmembrane peptide-induced lipid sorting and mechanism of Lalpha-to-inverted phase transition using coarse-grain molecular dynamics.

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Simulation studies of protein-induced bilayer deformations, and lipid-induced protein tilting, on a mesoscopic model for lipid bilayers with embedded proteins

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Insertion and assembly of membrane proteins via simulation.

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations.

1 reference

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21 January 2018

Mechanosensitive membrane channels in action

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Coarse-grained simulation: a high-throughput computational approach to membrane proteins

1 reference

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21 January 2018

The MARTINI force field: coarse grained model for biomolecular simulations

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

The MARTINI Coarse-Grained Force Field: Extension to Proteins.

1 reference

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21 January 2018

GROMACS: A message-passing parallel molecular dynamics implementation

1 reference

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21 January 2018

Toroidal pores formed by antimicrobial peptides show significant disorder.

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Dynamic -Helix Structure of Micelle-bound Human Amylin

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

The condensing effect of cholesterol in lipid bilayers

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Coarse-grained molecular dynamics studies of the concentration and size dependence of fifth- and seventh-generation PAMAM dendrimers on pore formation in DMPC bilayer

1 reference

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21 January 2018

Polarizable water model for the coarse-grained MARTINI force field

1 reference

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21 January 2018

DNA and lipid bilayers: self-assembly and insertion

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Self-assembling of peptide/membrane complexes by atomistic molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Coarse-grained MD simulations of membrane protein-bilayer self-assembly.

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

GridMAT-MD: a grid-based membrane analysis tool for use with molecular dynamics

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Thermodynamic analysis of the effect of cholesterol on dipalmitoylphosphatidylcholine lipid membranes

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Inhibitors can arrest the membrane activity of human islet amyloid polypeptide independently of amyloid formation

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Calcium-activated membrane interaction of the islet amyloid polypeptide: implications in the pathogenesis of type II diabetes mellitus

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Effect of cholesterol on the structure of a phospholipid bilayer

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Advances in the characterization of supported lipid films with the atomic force microscope

1 reference

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21 January 2018

Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol.

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

1 reference

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21 January 2018

Conserved and Cooperative Assembly of Membrane-Bound α-Helical States of Islet Amyloid Polypeptide†

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Coarse grain models and the computer simulation of soft materials

1 reference

https://api.crossref.org/works/10.1103%2FPHYSREVE.84.051922

21 January 2018

Identifiers

10.1103/PHYSREVE.84.051922

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

2011PhRvE..84e1922X

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 May 2018

http://europepmc.org/abstract/MED/22181459

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