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Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia

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Europe PubMed Central

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21 August 2017

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Europe PubMed Central

Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

1 reference

based on heuristic

inferred from title

maturity-onset diabetes of the young

1 reference

based on heuristic

inferred from title

Christine Bellanné-Chantelot

5

object named as

Christine Bellanné-Chantelot

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

object named as

Anna L Gloyn

7

0 references

object named as

Sian Ellard

6

0 references

author name string

Kara K Osbak

1

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Kevin Colclough

2

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Cecile Saint-Martin

3

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Nicola L Beer

4

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

publication date

1 November 2009

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

30

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

1512-1526

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Semi-automated unidirectional sequence analysis for mutation detection in a clinical diagnostic setting.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Genetics of neonatal hyperinsulinism.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Diagnosis of MODY in the offspring of parents with insulin-dependent and non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Structural instability of mutant beta-cell glucokinase: implications for the molecular pathogenesis of maturity-onset diabetes of the young (type-2).

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Mammalian glucokinase and its gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

High prevalence of glucokinase mutations in Italian children with MODY. Influence on glucose tolerance, first-phase insulin response, insulin sensitivity and BMI.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Identification of eight new mutations in the GCK gene by DHPLC screening in a Spanish population.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

21 January 2018

Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that glucokinase regulatory protein is expressed and interacts with glucokinase in rat brain

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic beta-cells: evidence for cellular instability of catalytic activity

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Activating mutations in the ABCC8 gene in neonatal diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Animal Model for Maturity-onset Diabetes of the Young Generated by Disruption of the Mouse Glucokinase Gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partner

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Nine novel mutations in maturity-onset diabetes of the young (MODY) candidate genes in 22 Spanish families

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Are glucokinase mutations associated with low triglycerides?

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

SAR, pharmacokinetics, safety, and efficacy of glucokinase activating 2-(4-sulfonylphenyl)-N-thiazol-2-ylacetamides: discovery of PSN-GK1.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Allosteric activation of human glucokinase by free polyubiquitin chains and its ubiquitin-dependent cotranslational proteasomal degradation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Routine mutation screening of HNF-1alpha and GCK genes in MODY diagnosis: how effective are the techniques of DHPLC and direct sequencing used in combination?

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY)

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel mutations in GCK and HNF1A genes in Italian families with MODY phenotype

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase gene variants in the common form of NIDDM

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Activating glucokinase (GCK) mutations as a cause of medically responsive congenital hyperinsulinism: prevalence in children and characterisation of a novel GCK mutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase mutations in young children with hyperglycemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Mild fasting hyperglycemia in children: high rate of glucokinase mutations and some risk of developing type 1 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic and clinical characterisation of maturity-onset diabetes of the young in Spanish families.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Family with autosomal dominant hyperinsulinism associated with A456V mutation in the glucokinase gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Diagnostic heterogeneity of diabetes in lean young adults: classification based on immunological and genetic parameters

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

HLA genotyping supports a nonautoimmune etiology in patients diagnosed with diabetes under the age of 6 months

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel glucokinase activator modulates pancreatic islet and hepatocyte function

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A high prevalence of glucokinase mutations in gestational diabetic subjects selected by clinical criteria.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Best practice guidelines for the molecular genetic diagnosis of maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Partial and whole gene deletion mutations of the GCK and HNF1A genes in maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical characterization of novel glucokinase mutations isolated from Spanish maturity-onset diabetes of the young (MODY2) patients.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Aetiological heterogeneity of asymptomatic hyperglycaemia in children and adolescents

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A Novel Mutation in Exon 5 of the Glucokinase Gene in an Argentinian Family with Maturity Onset Diabetes of the Young

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Strategies for the collection of sibling-pair data for genetic studies in type 2 (non-insulin-dependent) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Low prevalence of MODY2 and MODY3 mutations in Brazilian individuals with clinical MODY phenotype

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Haploinsufficiency at GCK gene is not a frequent event in MODY2 patients.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a novel beta-cell glucokinase (GCK) promoter mutation (-71G>C) that modulates GCK gene expression through loss of allele-specific Sp1 binding causing mild fasting hyperglycemia in humans

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Familial hyperinsulinism caused by an activating glucokinase mutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Defining the genetic aetiology of monogenic diabetes can improve treatment

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Complete glucokinase deficiency is not a common cause of permanent neonatal diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase (GCK) and other susceptibility genes for beta-cell dysfunction: the candidate approach.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevalence of GCK mutations in individuals screened for fasting hyperglycaemia.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Early-onset Type II diabetes mellitus in Italian families due to mutations in the genes encoding hepatic nuclear factor 1 alpha and glucokinase

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase activators for the potential treatment of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Allosteric activators of glucokinase: potential role in diabetes therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Small molecule glucokinase activators as glucose lowering agents: a new paradigm for diabetes therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Six mutations in the glucokinase gene identified in MODY by using a nonradioactive sensitive screening technique

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the glucokinase gene of the fetus result in reduced birth weight

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Linkage of type 2 diabetes to the glucokinase gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevalence and clinical phenotype of the p.Val226Met glucokinase gene mutation in French Canadians in Quebec, Canada.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic and clinical characteristics of Korean maturity-onset diabetes of the young (MODY) patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery of potent and orally active 3-alkoxy-5-phenoxy-N-thiazolyl benzamides as novel allosteric glucokinase activators

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved metabolic disorders of insulin receptor-deficient mice by transgenic overexpression of glucokinase in the liver

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Half of clinically defined maturity-onset diabetes of the young patients in Denmark do not have mutations in HNF4A, GCK, and TCF1.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Nonsense mutation of glucokinase gene in late-onset non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A randomized controlled trial using glycemic plus fetal ultrasound parameters versus glycemic parameters to determine insulin therapy in gestational diabetes with fasting hyperglycemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel nonsense mutation in GCK exon 9 co-segregates with diabetes phenotype.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase mutations in a phenotypically selected multiethnic group of women with a history of gestational diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

High frequency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase gene mutation screening in Argentinean clinically characterized MODY patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Maturity-onset diabetes of the young in children with incidental hyperglycemia: a multicenter Italian study of 172 families

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase gene structure. Functional implications of molecular genetic studies

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of eight novel glucokinase mutations in Italian children with maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

HNF1alpha mutations are present in half of clinically defined MODY patients in South-Brazilian individuals

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of the ATP-binding site in human pancreatic glucokinase

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Assessing the potential of glucokinase activators in diabetes therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Design of a potent, soluble glucokinase activator with excellent in vivo efficacy.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Diagnostic difficulties in glucokinase hyperinsulinism.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel glucokinase mutation in a boy with maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): different glucokinase defects lead to a common phenotype

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevalence of maturity-onset diabetes of the young mutations in Brazilian families with autosomal-dominant early-onset type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of small-molecule glucokinase activator on glucose metabolism and beta-cell mass

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of glucokinase mutation in subjects with post-renal transplantation diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular genetics of diabetes mellitus in Chinese subjects: identification of mutations in glucokinase and hepatocyte nuclear factor-1alpha genes in patients with early-onset type 2 diabetes mellitus/MODY.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Familial early-onset type 2 diabetes in Chinese patients: obesity and genetics have more significant roles than autoimmunity

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of Increased Glucokinase Gene Copy Number on Glucose Homeostasis and Hepatic Glucose Metabolism

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Neonatal diabetes mellitus due to complete glucokinase deficiency

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-function analysis of the alpha5 and the alpha13 helices of human glucokinase: description of two novel activating mutations.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase thermolability and hepatic regulatory protein binding are essential factors for predicting the blood glucose phenotype of missense mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Six novel mutations in the GCK gene in MODY patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Permanent neonatal diabetes in an Asian infant.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Variants in MTNR1B influence fasting glucose levels

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Effective treatment with oral sulfonylureas in patients with diabetes due to sulfonylurea receptor 1 (SUR1) mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Permanent neonatal diabetes caused by a homozygous nonsense mutation in the glucokinase gene.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Diagnostic screening of MODY2/GCK mutations in the Norwegian MODY Registry

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

High prevalence of a missense mutation of the glucokinase gene in gestational diabetic patients due to a founder-effect in a local population

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Extremes of clinical and enzymatic phenotypes in children with hyperinsulinism caused by glucokinase activating mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

MLPA and MAPH: new techniques for detection of gene deletions

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Common variants in MODY genes increase the risk of gestational diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical characteristics of mutation carriers in a large family with glucokinase diabetes (MODY2).

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the glucokinase gene of the fetus result in reduced placental weight

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

The long-term impact on offspring of exposure to hyperglycaemia in utero due to maternal glucokinase gene mutations.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Referral rates for diagnostic testing support an incidence of permanent neonatal diabetes in three European countries of at least 1 in 260,000 live births

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical evidence for the presence of glucokinase in the gonadotropes and thyrotropes of the anterior pituitary gland of rat and monkey

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Pregnancy outcome in patients with raised blood glucose due to a heterozygous glucokinase gene mutation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of glucokinase mutations in subjects with gestational diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin gene mutations as a cause of permanent neonatal diabetes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

The genetic abnormality in the beta cell determines the response to an oral glucose load

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of 21 novel glucokinase (GCK) mutations in UK and European Caucasians with maturity-onset diabetes of the young (MODY)

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase gene mutations: structural and genotype-phenotype analyses in MODY children from South Italy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of novel GCK and HNF1A/TCF1 mutations and polymorphisms in German families with maturity-onset diabetes of the young (MODY).

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term treatment of persistent hyperinsulinaemic hypoglycaemia of infancy with diazoxide: a retrospective review of 77 cases and analysis of efficacy-predicting criteria.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Permanent neonatal diabetes mellitus caused by a novel homozygous (T168A) glucokinase (GCK) mutation: initial response to oral sulphonylurea therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene duplications resulting in over expression of glucokinase are not a common cause of hypoglycaemia of infancy in humans

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucokinase gene mutations are not a common cause of permanent neonatal diabetes in France

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of novel and recurrent glucokinase mutations in Belgian and Luxembourg maturity onset diabetes of the young patients.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Heterogeneity in disease severity in a family with a novel G68V GCK activating mutation causing persistent hyperinsulinaemic hypoglycaemia of infancy.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic and clinical characteristics of maturity-onset diabetes of the young in Chinese patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

A glucose sensor role for glucokinase in anterior pituitary cells.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular genetics of MODY in Germany

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Linkage Analysis and Molecular Scanning of Glucokinase Gene in NIDDM Families

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

GCK and HNF1alpha mutations and polymorphisms in Polish women with gestational diabetes.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21110

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HUMU.21110

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

ResearchGate publication ID

0 references

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