(Q37615342)

21 August 2017

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title

Chemically modified cell-penetrating peptides for the delivery of nucleic acids (English)

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21 August 2017

1

Maarja Mäe

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Ülo Langel

4

object named as

Ulo Langel

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Samir El Andaloussi

2

object named as

Samir El Andaloussi

1 reference

21 August 2017

Maarja Mäe

1

1 reference

21 August 2017

Taavi Lehto

3

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21 August 2017

Ulo Langel

4

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21 August 2017

language of work or name

English

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publication date

1 November 2009

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Expert Opinion on Drug Delivery

21 August 2017

published in

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21 August 2017

volume

6

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21 August 2017

issue

11

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21 August 2017

page(s)

1195-1205

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Nonviral gene delivery: what we know and what is next

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

21 January 2018

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The membrane repair response masks membrane disturbances caused by cell-penetrating peptide uptake

21 January 2018

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Differentiation restricted endocytosis of cell penetrating peptides in MDCK cells corresponds with activities of Rho-GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

First step of the cell-penetrating peptide mechanism involves Rac1 GTPase-dependent actin-network remodelling

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425240903213688

Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells

21 January 2018

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Mechanistic aspects of CPP-mediated intracellular drug delivery: relevance of CPP self-assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors.

21 January 2018

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Progress in antisense technology.

21 January 2018

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Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides

21 January 2018

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microRNAs: tiny regulators with great potential

21 January 2018

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Regulation of gene expression with double-stranded phosphorothioate oligonucleotides

21 January 2018

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

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Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro

21 January 2018

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Delivery of bioactive molecules into the cell: the Trojan horse approach

21 January 2018

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Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

21 January 2018

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Modulation of the typical multidrug resistance phenotype by targeting the MED-1 region of human MDR1 promoter

21 January 2018

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TP10, a delivery vector for decoy oligonucleotides targeting the Myc protein.

21 January 2018

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Cellular delivery of a double-stranded oligonucleotide NFkappaB decoy by hybridization to complementary PNA linked to a cell-penetrating peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Efficient splicing correction by PNA conjugation to an R6-Penetratin delivery peptide

21 January 2018

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Induction of splice correction by cell-penetrating peptide nucleic acids

21 January 2018

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Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development

21 January 2018

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Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions

21 January 2018

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HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers.

21 January 2018

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Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD.

21 January 2018

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Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Effective exon skipping and restoration of dystrophin expression by peptide nucleic acid antisense oligonucleotides in mdx mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425240903213688

Transvascular delivery of small interfering RNA to the central nervous system.

21 January 2018

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Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

21 January 2018

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Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425240903213688

RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity.

21 January 2018

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A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Cellular siRNA delivery mediated by a cell-permeant RNA-binding protein and photoinduced RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Delivery of short interfering RNA using endosomolytic cell-penetrating peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Enhanced gene expression by a novel stearylated INF7 peptide derivative through fusion independent endosomal escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Biophysical and biological studies of end-group-modified derivatives of Pep-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

A non-covalent peptide-based strategy for protein and peptide nucleic acid transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Cell-surface thiols affect cell entry of disulfide-conjugated peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Improved cellular activity of antisense peptide nucleic acids by conjugation to a cationic peptide-lipid (CatLip) domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Stearylated arginine-rich peptides: a new class of transfection systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: enhanced cellular association by hydrophobic core formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Octaarginine-modified multifunctional envelope-type nano device for siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Evaluation of transportan 10 in PEI mediated plasmid delivery assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Enhanced delivery of cell-penetrating peptide-peptide nucleic acid conjugates by endosomal disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Structural requirements for cellular uptake and antisense activity of peptide nucleic acids conjugated with various peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Improved cell-penetrating peptide-PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

A non-covalent peptide-based carrier for in vivo delivery of DNA mimics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

A Comprehensive Model for the Cellular Uptake of Cationic Cell-penetrating Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

A Novel Cell-penetrating Peptide, M918, for Efficient Delivery of Proteins and Peptide Nucleic Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903213688

10.1517/17425240903213688

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference