(Q37616866)

21 August 2017

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title

Protein-protein interaction networks: how can a hub protein bind so many different partners? (English)

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protein-protein interaction

21 August 2017

main subject

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2

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21 August 2017

3

Ruth Nussinov

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21 August 2017

1

Chung-Jung Tsai

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21 August 2017

publication date

1 December 2009

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21 August 2017

number of pages

7

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Trends in Biochemical Sciences

inferred from page(s)

published in

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21 August 2017

volume

34

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21 August 2017

issue

12

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21 August 2017

page(s)

594-600

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Dynamic Complex Formation During the Yeast Cell Cycle

21 August 2017

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12 December 2020

Structural basis of Dscam isoform specificity

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12 December 2020

Alternative translation initiation further increases the molecular and functional diversity of ion channels

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12 December 2020

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12 December 2020

Conformational switching upon phosphorylation: a predictive framework based on energy landscape principles.

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12 December 2020

Variations in clique and community patterns in protein structures during allosteric communication: investigation of dynamically equilibrated structures of methionyl tRNA synthetase complexes.

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12 December 2020

Emerging roles of BRCA1 alternative splicing

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12 December 2020

Folding funnels, binding funnels, and protein function

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12 December 2020

Relating three-dimensional structures to protein networks provides evolutionary insights

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12 December 2020

Towards inferring time dimensionality in protein-protein interaction networks by integrating structures: the p53 example

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12 December 2020

Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

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12 December 2020

A "silent" polymorphism in the MDR1 gene changes substrate specificity

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12 December 2020

Drug-therapy networks and the prediction of novel drug targets

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12 December 2020

Functional characterization of p53beta and p53gamma, two isoforms of the tumor suppressor p53.

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Network pharmacology: the next paradigm in drug discovery

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Towards drugs targeting multiple proteins in a systems biology approach

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p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms

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Folding and binding cascades: dynamic landscapes and population shifts

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12 December 2020

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

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12 December 2020

BIOCHEMISTRY: How Do Proteins Interact?

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12 December 2020

Cataloging and organizing p73 interactions in cell cycle arrest and apoptosis

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12 December 2020

What properties characterize the hub proteins of the protein-protein interaction network of Saccharomyces cerevisiae?

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12 December 2020

A protein domain-based interactome network for C. elegans early embryogenesis

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12 December 2020

Why do hubs tend to be essential in protein networks?

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12 December 2020

Characterization of protein hubs by inferring interacting motifs from protein interactions

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12 December 2020

Synonymous mutations and ribosome stalling can lead to altered folding pathways and distinct minima

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12 December 2020

Combinatorial control of exon recognition.

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12 December 2020

Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium

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12 December 2020

p53 isoforms - a conspiracy to kidnap p53 tumor suppressor activity?

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12 December 2020

Functional organization of the yeast proteome by systematic analysis of protein complexes

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Human genome: end of the beginning

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12 December 2020

Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

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Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution

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Alternative splicing in human transcriptome: functional and structural influence on proteins.

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Energetic determinants of protein binding specificity: insights into protein interaction networks

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12 December 2020

Molecular diversity of Dscam: recognition of molecular identity in neuronal wiring

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Evidence for dynamically organized modularity in the yeast protein-protein interaction network

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Evolvability and hierarchy in rewired bacterial gene networks

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Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

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Coding region structural heterogeneity and turnover of transcription start sites contribute to divergence in expression between duplicate genes

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12 December 2020

Principles of protein-protein interactions: what are the preferred ways for proteins to interact?

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Finishing the euchromatic sequence of the human genome

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Allosteric communication occurs via networks of tertiary and quaternary motions in proteins

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Protein-protein interactions: organization, cooperativity and mapping in a bottom-up Systems Biology approach

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SnapShot: p53 posttranslational modifications

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12 December 2020

How perfect can protein interactomes be?

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12 December 2020

Distributions of exons and introns in the human genome

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12 December 2020

10.1016/J.TIBS.2009.07.007

Identifiers

DOI

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21 August 2017

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