(Q37617410)

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The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon

scientific article published on March 2014

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scholarly article

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PMC publication ID

21 August 2017

The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon (English)

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Europe PubMed Central

PMC publication ID

21 August 2017

oligodendrocyte

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Masato Nakafuku

10

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9 June 2020

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Lisa A Ehrman

1

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9 June 2020

Diana Nardini

2

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9 June 2020

Sarah Ehrman

3

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9 June 2020

Tilat A Rizvi

4

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9 June 2020

James Gulick

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9 June 2020

Maike Krenz

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9 June 2020

Biplab Dasgupta

7

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9 June 2020

Jeffrey Robbins

8

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9 June 2020

Nancy Ratner

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9 June 2020

Ronald R Waclaw

11

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9 June 2020

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1 March 2014

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21 August 2017

Journal of Neuroscience

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9 June 2020

34

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9 June 2020

10

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9 June 2020

3767-3778

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9 June 2020

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3942589/fullTextXML

based on heuristic

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Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

The homeobox gene Gsx2 controls the timing of oligodendroglial fate specification in mouse lateral ganglionic eminence progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

PTPN11-associated mutations in the heart: has LEOPARD changed Its RASpots?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Olig2-dependent developmental fate switch of NG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

SHP-2 promotes the maturation of oligodendrocyte precursor cells through Akt and ERK1/2 signaling in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Developmental genetics of vertebrate glial-cell specification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Developmental origin of the neuronal subtypes that comprise the amygdalar fear circuit in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Protein tyrosine phosphatase activity in the neural crest is essential for normal heart and skull development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Genotype differences in cognitive functioning in Noonan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Constitutively active Akt induces enhanced myelination in the CNS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism

1 reference

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23 August 2017

The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Transcriptional control of oligodendrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome

1 reference

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23 August 2017

Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Stops along the RAS pathway in human genetic disease

1 reference

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23 August 2017

The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons

1 reference

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23 August 2017

Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage.

1 reference

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23 August 2017

Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation

1 reference

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23 August 2017

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty

1 reference

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23 August 2017

For the long run: maintaining germinal niches in the adult brain

1 reference

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23 August 2017

Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants

1 reference

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23 August 2017

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

1 reference

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23 August 2017

A long, remarkable journey: tangential migration in the telencephalon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

23 August 2017

Recombination within the myelin basic protein gene created the dysmyelinating shiverer mouse mutation

1 reference

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23 August 2017

ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities

1 reference

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25 June 2018

MEK Is a Key Regulator of Gliogenesis in the Developing Brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

Long term memory profile of disorders associated with dysregulation of the RAS-MAPK signaling cascade.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

A crucial role for Olig2 in white matter astrocyte development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

Neural crest cells retain multipotential characteristics in the developing valves and label the cardiac conduction system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

Psychological profile of children with Noonan syndrome.

1 reference

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1 September 2018

Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3942589

1 September 2018

Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/24599474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3515-13.2014

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599474%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599474%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24599474%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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